Promising photocatalytic and antimicrobial activity of novel capsaicin coated cobalt ferrite nanocatalyst
Abstract In this study, CoFe2O4 nanoparticles were prepared by the co-precipitation method then surface modified with Capsaicin (Capsicum annuum ssp.). The virgin CoFe2O4 NPs and Capsaicin-coated CoFe2O4 NPs (CPCF NPs) were characterized by XRD, FTIR, SEM, and TEM. The antimicrobial potential and ph...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Nature Portfolio
2023-04-01
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| Series: | Scientific Reports |
| Online Access: | https://doi.org/10.1038/s41598-023-32323-y |
| _version_ | 1797853889197768704 |
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| author | Ahmed M. El-Khawaga Mohamed A. Elsayed Yosri A. Fahim Rasha E. Shalaby |
| author_facet | Ahmed M. El-Khawaga Mohamed A. Elsayed Yosri A. Fahim Rasha E. Shalaby |
| author_sort | Ahmed M. El-Khawaga |
| collection | DOAJ |
| description | Abstract In this study, CoFe2O4 nanoparticles were prepared by the co-precipitation method then surface modified with Capsaicin (Capsicum annuum ssp.). The virgin CoFe2O4 NPs and Capsaicin-coated CoFe2O4 NPs (CPCF NPs) were characterized by XRD, FTIR, SEM, and TEM. The antimicrobial potential and photocatalytic degradation efficiencies of the prepared samples via Fuchsine basic (FB) were investigated. The results revealed that CoFe2O4 NPs have spherical shapes and their diameter varied from 18.0 to 30.0 nm with an average particle size of 25.0 nm. Antimicrobial activity was tested on Gram-positive (S. aureusATCC 52923) and Gram-negative (E. coli ATCC 52922) by disk diffusion and broth dilution methods to determine the zone of inhibition (ZOI) and minimum inhibitory concentration (MIC), respectively. UV-assisted photocatalytic degradation of FB was examined. Various parameters affecting the photocatalytic efficiency such as pH, initial concentration of FB, and dose of nanocatalyst were studied. The in-vitro ZOI and MIC results verified that CPCF NPs were more active upon Gram-Positive S. aureus ATCC 52923 (23.0 mm ZOI and 0.625 μg/ml MIC) than Gram-Negative E. coli ATCC 52922 (17.0 mm ZOI and 1.250 μg/ml MIC). Results obtained from the photocatalytic activity indicated that the maximum FB removal achieving 94.6% in equilibrium was observed using 20.0 mg of CPCF NPS at pH 9.0. The synthesized CPCF NPs were effective in the removal of FB and also as potent antimicrobial agent against both Gram-positive and Gram-negative bacteria with potential medical and environmental applications. |
| first_indexed | 2024-04-09T19:58:06Z |
| format | Article |
| id | doaj.art-f09f9d225fef4dec941036d4c8f79ff1 |
| institution | Directory Open Access Journal |
| issn | 2045-2322 |
| language | English |
| last_indexed | 2024-04-09T19:58:06Z |
| publishDate | 2023-04-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Scientific Reports |
| spelling | doaj.art-f09f9d225fef4dec941036d4c8f79ff12023-04-03T05:23:10ZengNature PortfolioScientific Reports2045-23222023-04-0113111510.1038/s41598-023-32323-yPromising photocatalytic and antimicrobial activity of novel capsaicin coated cobalt ferrite nanocatalystAhmed M. El-Khawaga0Mohamed A. Elsayed1Yosri A. Fahim2Rasha E. Shalaby3Department of Basic Medical Sciences, Faculty of Medicine, Galala UniversityChemical Engineering Department, Military Technical College (MTC)Department of Basic Medical Sciences, Faculty of Medicine, Galala UniversityDepartment of Basic Medical Sciences, Faculty of Medicine, Galala UniversityAbstract In this study, CoFe2O4 nanoparticles were prepared by the co-precipitation method then surface modified with Capsaicin (Capsicum annuum ssp.). The virgin CoFe2O4 NPs and Capsaicin-coated CoFe2O4 NPs (CPCF NPs) were characterized by XRD, FTIR, SEM, and TEM. The antimicrobial potential and photocatalytic degradation efficiencies of the prepared samples via Fuchsine basic (FB) were investigated. The results revealed that CoFe2O4 NPs have spherical shapes and their diameter varied from 18.0 to 30.0 nm with an average particle size of 25.0 nm. Antimicrobial activity was tested on Gram-positive (S. aureusATCC 52923) and Gram-negative (E. coli ATCC 52922) by disk diffusion and broth dilution methods to determine the zone of inhibition (ZOI) and minimum inhibitory concentration (MIC), respectively. UV-assisted photocatalytic degradation of FB was examined. Various parameters affecting the photocatalytic efficiency such as pH, initial concentration of FB, and dose of nanocatalyst were studied. The in-vitro ZOI and MIC results verified that CPCF NPs were more active upon Gram-Positive S. aureus ATCC 52923 (23.0 mm ZOI and 0.625 μg/ml MIC) than Gram-Negative E. coli ATCC 52922 (17.0 mm ZOI and 1.250 μg/ml MIC). Results obtained from the photocatalytic activity indicated that the maximum FB removal achieving 94.6% in equilibrium was observed using 20.0 mg of CPCF NPS at pH 9.0. The synthesized CPCF NPs were effective in the removal of FB and also as potent antimicrobial agent against both Gram-positive and Gram-negative bacteria with potential medical and environmental applications.https://doi.org/10.1038/s41598-023-32323-y |
| spellingShingle | Ahmed M. El-Khawaga Mohamed A. Elsayed Yosri A. Fahim Rasha E. Shalaby Promising photocatalytic and antimicrobial activity of novel capsaicin coated cobalt ferrite nanocatalyst Scientific Reports |
| title | Promising photocatalytic and antimicrobial activity of novel capsaicin coated cobalt ferrite nanocatalyst |
| title_full | Promising photocatalytic and antimicrobial activity of novel capsaicin coated cobalt ferrite nanocatalyst |
| title_fullStr | Promising photocatalytic and antimicrobial activity of novel capsaicin coated cobalt ferrite nanocatalyst |
| title_full_unstemmed | Promising photocatalytic and antimicrobial activity of novel capsaicin coated cobalt ferrite nanocatalyst |
| title_short | Promising photocatalytic and antimicrobial activity of novel capsaicin coated cobalt ferrite nanocatalyst |
| title_sort | promising photocatalytic and antimicrobial activity of novel capsaicin coated cobalt ferrite nanocatalyst |
| url | https://doi.org/10.1038/s41598-023-32323-y |
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