Protein-Losing Enteropathy Resolved by Helicobacter pylori Eradication

Protein-losing enteropathy (PLGE) is an uncommon condition with a multifactorial origin, that is characterized by excessive loss of serum proteins into the gastrointestinal tract, resulting in hypoproteinaemia and oedema.  The authors present the case of a 24-year-old man admitted to hospital for a...

Full description

Bibliographic Details
Main Authors: Bruno Sousa, Rosa Alves, Catarina Pestana Santos, Tiago Judas Matos
Format: Article
Language:English
Published: SMC MEDIA SRL 2022-05-01
Series:European Journal of Case Reports in Internal Medicine
Subjects:
Online Access:https://www.ejcrim.com/index.php/EJCRIM/article/view/3312
_version_ 1818240469415493632
author Bruno Sousa
Rosa Alves
Catarina Pestana Santos
Tiago Judas Matos
author_facet Bruno Sousa
Rosa Alves
Catarina Pestana Santos
Tiago Judas Matos
author_sort Bruno Sousa
collection DOAJ
description Protein-losing enteropathy (PLGE) is an uncommon condition with a multifactorial origin, that is characterized by excessive loss of serum proteins into the gastrointestinal tract, resulting in hypoproteinaemia and oedema.  The authors present the case of a 24-year-old man admitted to hospital for a 2-month history of lower extremity oedema and diarrhoea with a secretory pattern. Blood analysis revealed hypoalbuminaemia and iron deficiency anaemia. Liver disease and severe proteinuria were excluded as possible aetiologies. Upper gastrointestinal endoscopy revealed signs of chronic Helicobacter pylori gastritis. After completion of H. pylori eradication, the patient had complete resolution of clinical and laboratory abnormalities. The results suggest the need to consider less frequent aetiologies for peripheral oedema and hypoproteinaemia, such as PLGE, especially those caused by prevalent bacterial agents like H. pylori.
first_indexed 2024-12-12T13:13:56Z
format Article
id doaj.art-f0a21d54fa28491b87eb32f9961ea609
institution Directory Open Access Journal
issn 2284-2594
language English
last_indexed 2024-12-12T13:13:56Z
publishDate 2022-05-01
publisher SMC MEDIA SRL
record_format Article
series European Journal of Case Reports in Internal Medicine
spelling doaj.art-f0a21d54fa28491b87eb32f9961ea6092022-12-22T00:23:28ZengSMC MEDIA SRLEuropean Journal of Case Reports in Internal Medicine2284-25942022-05-0110.12890/2022_0033122847Protein-Losing Enteropathy Resolved by Helicobacter pylori EradicationBruno Sousa0Rosa Alves1Catarina Pestana Santos2Tiago Judas Matos3Department of Internal Medicine, Hospital Garcia de Orta, Almada, Lisbon, PortugalDepartment of Internal Medicine, Hospital Garcia de Orta, Almada, Lisbon, PortugalDepartment of Internal Medicine, Hospital Garcia de Orta, Almada, Lisbon, PortugalDepartment of Internal Medicine, Hospital Garcia de Orta, Almada, Lisbon, PortugalProtein-losing enteropathy (PLGE) is an uncommon condition with a multifactorial origin, that is characterized by excessive loss of serum proteins into the gastrointestinal tract, resulting in hypoproteinaemia and oedema.  The authors present the case of a 24-year-old man admitted to hospital for a 2-month history of lower extremity oedema and diarrhoea with a secretory pattern. Blood analysis revealed hypoalbuminaemia and iron deficiency anaemia. Liver disease and severe proteinuria were excluded as possible aetiologies. Upper gastrointestinal endoscopy revealed signs of chronic Helicobacter pylori gastritis. After completion of H. pylori eradication, the patient had complete resolution of clinical and laboratory abnormalities. The results suggest the need to consider less frequent aetiologies for peripheral oedema and hypoproteinaemia, such as PLGE, especially those caused by prevalent bacterial agents like H. pylori.https://www.ejcrim.com/index.php/EJCRIM/article/view/3312protein losing-enteropathyoedemahypoalbuminaemiahelicobacter pylori
spellingShingle Bruno Sousa
Rosa Alves
Catarina Pestana Santos
Tiago Judas Matos
Protein-Losing Enteropathy Resolved by Helicobacter pylori Eradication
European Journal of Case Reports in Internal Medicine
protein losing-enteropathy
oedema
hypoalbuminaemia
helicobacter pylori
title Protein-Losing Enteropathy Resolved by Helicobacter pylori Eradication
title_full Protein-Losing Enteropathy Resolved by Helicobacter pylori Eradication
title_fullStr Protein-Losing Enteropathy Resolved by Helicobacter pylori Eradication
title_full_unstemmed Protein-Losing Enteropathy Resolved by Helicobacter pylori Eradication
title_short Protein-Losing Enteropathy Resolved by Helicobacter pylori Eradication
title_sort protein losing enteropathy resolved by helicobacter pylori eradication
topic protein losing-enteropathy
oedema
hypoalbuminaemia
helicobacter pylori
url https://www.ejcrim.com/index.php/EJCRIM/article/view/3312
work_keys_str_mv AT brunosousa proteinlosingenteropathyresolvedbyhelicobacterpylorieradication
AT rosaalves proteinlosingenteropathyresolvedbyhelicobacterpylorieradication
AT catarinapestanasantos proteinlosingenteropathyresolvedbyhelicobacterpylorieradication
AT tiagojudasmatos proteinlosingenteropathyresolvedbyhelicobacterpylorieradication