Pain behavior to electroacupuncture in rabbit tooth pulp
Aim: The aim of this study was to verify the pain behavior to electroacupuncture (EACP) in rabbit tooth-pulp assay. Methods: Albino rabbits weighing 1.5-2.0 kg) were pretreated with saline or morphine (5mg/kg, e.v.) 10 min before the nociceptive test (NT). In another group, EACP (rectangular pulses,...
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| Format: | Article |
| Language: | English |
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Universidade Estadual de Campinas
2015-11-01
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| Series: | Brazilian Journal of Oral Sciences |
| Subjects: | |
| Online Access: | https://periodicos.sbu.unicamp.br/ojs/index.php/bjos/article/view/8641717 |
| _version_ | 1818437053824630784 |
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| author | Delane Viana Gondim Krishnamurti de Morais Carvalho Mariana Lima Vale |
| author_facet | Delane Viana Gondim Krishnamurti de Morais Carvalho Mariana Lima Vale |
| author_sort | Delane Viana Gondim |
| collection | DOAJ |
| description | Aim: The aim of this study was to verify the pain behavior to electroacupuncture (EACP) in rabbit tooth-pulp assay. Methods: Albino rabbits weighing 1.5-2.0 kg) were pretreated with saline or morphine (5mg/kg, e.v.) 10 min before the nociceptive test (NT). In another group, EACP (rectangular pulses, f1=2 Hz, f2=0.1 s, 3 mA) was applied in acupoints and sham points, before and during the NT. After 120 min, EACP was withdrawn and the nociceptive threshold was measured every 10 min until the initial nociceptive threshold was achieved. Results: EACP, using the Yintang, ST4 and ST5 acupoints, induced an increased in the nociceptive threshold and this effect persisted for up to 2 h, even after the removal of electric stimulation. Application of EACP at sham points did not show significant analgesic activity. The present results demonstrated that males presented a higher initial level of analgesia, but a poorer maintenance of analgesic effect after the EACP procedure, while females demonstrated a long lasting analgesic effect even after discontinuation of EACP. Conclusions: EACP presented an analgesic effect in a rabbit tooth pulp assay that was probably due to the release of endogenous opioids. The duration of this analgesic effect seems to be different for males and females. |
| first_indexed | 2024-12-14T17:18:34Z |
| format | Article |
| id | doaj.art-f0a24a2f772d49338c9c6d53fdd77873 |
| institution | Directory Open Access Journal |
| issn | 1677-3225 |
| language | English |
| last_indexed | 2024-12-14T17:18:34Z |
| publishDate | 2015-11-01 |
| publisher | Universidade Estadual de Campinas |
| record_format | Article |
| series | Brazilian Journal of Oral Sciences |
| spelling | doaj.art-f0a24a2f772d49338c9c6d53fdd778732022-12-21T22:53:23ZengUniversidade Estadual de CampinasBrazilian Journal of Oral Sciences1677-32252015-11-019410.20396/bjos.v9i4.8641717Pain behavior to electroacupuncture in rabbit tooth pulpDelane Viana Gondim0Krishnamurti de Morais Carvalho1Mariana Lima Vale2Federal University of CearáState University of CearáFederal University of Ceará, FortalezaAim: The aim of this study was to verify the pain behavior to electroacupuncture (EACP) in rabbit tooth-pulp assay. Methods: Albino rabbits weighing 1.5-2.0 kg) were pretreated with saline or morphine (5mg/kg, e.v.) 10 min before the nociceptive test (NT). In another group, EACP (rectangular pulses, f1=2 Hz, f2=0.1 s, 3 mA) was applied in acupoints and sham points, before and during the NT. After 120 min, EACP was withdrawn and the nociceptive threshold was measured every 10 min until the initial nociceptive threshold was achieved. Results: EACP, using the Yintang, ST4 and ST5 acupoints, induced an increased in the nociceptive threshold and this effect persisted for up to 2 h, even after the removal of electric stimulation. Application of EACP at sham points did not show significant analgesic activity. The present results demonstrated that males presented a higher initial level of analgesia, but a poorer maintenance of analgesic effect after the EACP procedure, while females demonstrated a long lasting analgesic effect even after discontinuation of EACP. Conclusions: EACP presented an analgesic effect in a rabbit tooth pulp assay that was probably due to the release of endogenous opioids. The duration of this analgesic effect seems to be different for males and females.https://periodicos.sbu.unicamp.br/ojs/index.php/bjos/article/view/8641717ElectroacupunctureTooth pulpAnalgesic effectEndogenous opioidsPain |
| spellingShingle | Delane Viana Gondim Krishnamurti de Morais Carvalho Mariana Lima Vale Pain behavior to electroacupuncture in rabbit tooth pulp Brazilian Journal of Oral Sciences Electroacupuncture Tooth pulp Analgesic effect Endogenous opioids Pain |
| title | Pain behavior to electroacupuncture in rabbit tooth pulp |
| title_full | Pain behavior to electroacupuncture in rabbit tooth pulp |
| title_fullStr | Pain behavior to electroacupuncture in rabbit tooth pulp |
| title_full_unstemmed | Pain behavior to electroacupuncture in rabbit tooth pulp |
| title_short | Pain behavior to electroacupuncture in rabbit tooth pulp |
| title_sort | pain behavior to electroacupuncture in rabbit tooth pulp |
| topic | Electroacupuncture Tooth pulp Analgesic effect Endogenous opioids Pain |
| url | https://periodicos.sbu.unicamp.br/ojs/index.php/bjos/article/view/8641717 |
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