Current advances in circulating inflammatory biomarkers in atherosclerosis and related cardio-cerebrovascular diseases
Atherosclerosis (AS) is a systemic chronic disease affecting both the coronary and cerebral arteries. Inflammation plays a key role in the initiation and progression of AS, and numerous inflammatory factors have been proposed as potential biomarkers. This article reviews recent research in studies o...
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| Format: | Article |
| Language: | English |
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Wiley
2017-12-01
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| Series: | Chronic Diseases and Translational Medicine |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2095882X17300713 |
| _version_ | 1811227315054575616 |
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| author | Jun-Xuan Lv Qi Kong Xin Ma |
| author_facet | Jun-Xuan Lv Qi Kong Xin Ma |
| author_sort | Jun-Xuan Lv |
| collection | DOAJ |
| description | Atherosclerosis (AS) is a systemic chronic disease affecting both the coronary and cerebral arteries. Inflammation plays a key role in the initiation and progression of AS, and numerous inflammatory factors have been proposed as potential biomarkers. This article reviews recent research in studies on major circulating inflammatory biomarkers to identify surrogates that may reflect processes associated with AS development and the risk of AS-related vascular events, such as Von Willebrand factor, lectin-like oxidized low-density-lipoprotein receptor-1, soluble urokinase plasminogen activator receptor, regulated upon activation, normal T-cell expressed and secreted, and microparticles, which may provide new perspectives for clinical AS evaluation and risk stratification. |
| first_indexed | 2024-04-12T09:39:31Z |
| format | Article |
| id | doaj.art-f0a36112a3344ffe82d688ae6d17c9a4 |
| institution | Directory Open Access Journal |
| issn | 2095-882X |
| language | English |
| last_indexed | 2024-04-12T09:39:31Z |
| publishDate | 2017-12-01 |
| publisher | Wiley |
| record_format | Article |
| series | Chronic Diseases and Translational Medicine |
| spelling | doaj.art-f0a36112a3344ffe82d688ae6d17c9a42022-12-22T03:38:07ZengWileyChronic Diseases and Translational Medicine2095-882X2017-12-013420721210.1016/j.cdtm.2017.09.002Current advances in circulating inflammatory biomarkers in atherosclerosis and related cardio-cerebrovascular diseasesJun-Xuan LvQi KongXin MaAtherosclerosis (AS) is a systemic chronic disease affecting both the coronary and cerebral arteries. Inflammation plays a key role in the initiation and progression of AS, and numerous inflammatory factors have been proposed as potential biomarkers. This article reviews recent research in studies on major circulating inflammatory biomarkers to identify surrogates that may reflect processes associated with AS development and the risk of AS-related vascular events, such as Von Willebrand factor, lectin-like oxidized low-density-lipoprotein receptor-1, soluble urokinase plasminogen activator receptor, regulated upon activation, normal T-cell expressed and secreted, and microparticles, which may provide new perspectives for clinical AS evaluation and risk stratification.http://www.sciencedirect.com/science/article/pii/S2095882X17300713AtherosclerosisPlaquesInflammatory biomarkersRisk factors |
| spellingShingle | Jun-Xuan Lv Qi Kong Xin Ma Current advances in circulating inflammatory biomarkers in atherosclerosis and related cardio-cerebrovascular diseases Chronic Diseases and Translational Medicine Atherosclerosis Plaques Inflammatory biomarkers Risk factors |
| title | Current advances in circulating inflammatory biomarkers in atherosclerosis and related cardio-cerebrovascular diseases |
| title_full | Current advances in circulating inflammatory biomarkers in atherosclerosis and related cardio-cerebrovascular diseases |
| title_fullStr | Current advances in circulating inflammatory biomarkers in atherosclerosis and related cardio-cerebrovascular diseases |
| title_full_unstemmed | Current advances in circulating inflammatory biomarkers in atherosclerosis and related cardio-cerebrovascular diseases |
| title_short | Current advances in circulating inflammatory biomarkers in atherosclerosis and related cardio-cerebrovascular diseases |
| title_sort | current advances in circulating inflammatory biomarkers in atherosclerosis and related cardio cerebrovascular diseases |
| topic | Atherosclerosis Plaques Inflammatory biomarkers Risk factors |
| url | http://www.sciencedirect.com/science/article/pii/S2095882X17300713 |
| work_keys_str_mv | AT junxuanlv currentadvancesincirculatinginflammatorybiomarkersinatherosclerosisandrelatedcardiocerebrovasculardiseases AT qikong currentadvancesincirculatinginflammatorybiomarkersinatherosclerosisandrelatedcardiocerebrovasculardiseases AT xinma currentadvancesincirculatinginflammatorybiomarkersinatherosclerosisandrelatedcardiocerebrovasculardiseases |