Hypoxia extends lifespan and neurological function in a mouse model of aging

There is widespread interest in identifying interventions that extend healthy lifespan. Chronic continuous hypoxia delays the onset of replicative senescence in cultured cells and extends lifespan in yeast, nematodes, and fruit flies. Here, we asked whether chronic continuous hypoxia is beneficial i...

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Bibliographic Details
Main Authors: Robert S. Rogers, Hong Wang, Timothy J. Durham, Jonathan A. Stefely, Norah A. Owiti, Andrew L. Markhard, Lev Sandler, Tsz-Leung To, Vamsi K. Mootha
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-05-01
Series:PLoS Biology
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10204955/?tool=EBI