Sex determination and Aedes population control
Abstract The global economic cost of Aedes-borne diseases, such as dengue, is estimated to be in the billions of dollars annually. In this scenario, a sustained vector control strategy is the only alternative to control dengue, as well as other diseases transmitted by Aedes, including Zika and chiku...
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| Format: | Article |
| Language: | English |
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BMC
2018-12-01
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| Series: | Parasites & Vectors |
| Subjects: | |
| Online Access: | http://link.springer.com/article/10.1186/s13071-018-3217-6 |
| _version_ | 1819278145415544832 |
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| author | Helena Rocha Corrêa de Araújo Bianca Burini Kojin Margareth Lara Capurro |
| author_facet | Helena Rocha Corrêa de Araújo Bianca Burini Kojin Margareth Lara Capurro |
| author_sort | Helena Rocha Corrêa de Araújo |
| collection | DOAJ |
| description | Abstract The global economic cost of Aedes-borne diseases, such as dengue, is estimated to be in the billions of dollars annually. In this scenario, a sustained vector control strategy is the only alternative to control dengue, as well as other diseases transmitted by Aedes, including Zika and chikungunya. The use of transgenic mosquitoes is a promising weapon in the improvement of approaches currently applied in Aedes aegypti control. Field trials using genetically modified mosquitoes for population control have been conducted and offer an excellent opportunity to evaluate what can be improved. In a mass-rearing mosquito facility, the absence of a transgenic line that produces male-only progeny is undoubtedly a limiting factor; thus, being able to manipulate sex determination in this species is a fundamental step for the success of this strategy. Likewise, the possibility of manipulation of the sex determination pathway opens-up a new opportunity for disease control. |
| first_indexed | 2024-12-24T00:07:21Z |
| format | Article |
| id | doaj.art-f0a7b19b98a045c4acba5291c55dae84 |
| institution | Directory Open Access Journal |
| issn | 1756-3305 |
| language | English |
| last_indexed | 2024-12-24T00:07:21Z |
| publishDate | 2018-12-01 |
| publisher | BMC |
| record_format | Article |
| series | Parasites & Vectors |
| spelling | doaj.art-f0a7b19b98a045c4acba5291c55dae842022-12-21T17:24:59ZengBMCParasites & Vectors1756-33052018-12-0111S210711310.1186/s13071-018-3217-6Sex determination and Aedes population controlHelena Rocha Corrêa de Araújo0Bianca Burini Kojin1Margareth Lara Capurro2Department of Parasitology, Institute of Biomedical Sciences, University of São PauloDepartment of Entomology, Texas A & M University, Minnie Belle Heep CenterDepartment of Parasitology, Institute of Biomedical Sciences, University of São PauloAbstract The global economic cost of Aedes-borne diseases, such as dengue, is estimated to be in the billions of dollars annually. In this scenario, a sustained vector control strategy is the only alternative to control dengue, as well as other diseases transmitted by Aedes, including Zika and chikungunya. The use of transgenic mosquitoes is a promising weapon in the improvement of approaches currently applied in Aedes aegypti control. Field trials using genetically modified mosquitoes for population control have been conducted and offer an excellent opportunity to evaluate what can be improved. In a mass-rearing mosquito facility, the absence of a transgenic line that produces male-only progeny is undoubtedly a limiting factor; thus, being able to manipulate sex determination in this species is a fundamental step for the success of this strategy. Likewise, the possibility of manipulation of the sex determination pathway opens-up a new opportunity for disease control.http://link.springer.com/article/10.1186/s13071-018-3217-6Aedes aegyptivector borne diseasesmass-rearing and population suppression |
| spellingShingle | Helena Rocha Corrêa de Araújo Bianca Burini Kojin Margareth Lara Capurro Sex determination and Aedes population control Parasites & Vectors Aedes aegypti vector borne diseases mass-rearing and population suppression |
| title | Sex determination and Aedes population control |
| title_full | Sex determination and Aedes population control |
| title_fullStr | Sex determination and Aedes population control |
| title_full_unstemmed | Sex determination and Aedes population control |
| title_short | Sex determination and Aedes population control |
| title_sort | sex determination and aedes population control |
| topic | Aedes aegypti vector borne diseases mass-rearing and population suppression |
| url | http://link.springer.com/article/10.1186/s13071-018-3217-6 |
| work_keys_str_mv | AT helenarochacorreadearaujo sexdeterminationandaedespopulationcontrol AT biancaburinikojin sexdeterminationandaedespopulationcontrol AT margarethlaracapurro sexdeterminationandaedespopulationcontrol |