Differences in the Association Among the Vitamin D Concentration, Dietary Macronutrient Consumption, and Metabolic Syndrome Depending on Pre- and Postmenopausal Status in Korean Women: A Cross-Sectional Study
Hyejin Chun,1 Gi Dae Kim,2 Miae Doo3 1Department of Family Medicine, CHA Bundang Medical Center, CHA University, Seongnam, Gyeonggi, 13496, Republic of Korea; 2Department of Food and Nutrition, Kyungnam University, Changwon, Gyeongnam 51767, Republic of Korea; 3Department of Food and Nutrition, Kuns...
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Dove Medical Press
2020-10-01
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| Series: | Diabetes, Metabolic Syndrome and Obesity |
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| Online Access: | https://www.dovepress.com/differences-in-the-association-among-the-vitamin-d-concentration-dieta-peer-reviewed-article-DMSO |
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| author | Chun H Kim GD Doo M |
| author_facet | Chun H Kim GD Doo M |
| author_sort | Chun H |
| collection | DOAJ |
| description | Hyejin Chun,1 Gi Dae Kim,2 Miae Doo3 1Department of Family Medicine, CHA Bundang Medical Center, CHA University, Seongnam, Gyeonggi, 13496, Republic of Korea; 2Department of Food and Nutrition, Kyungnam University, Changwon, Gyeongnam 51767, Republic of Korea; 3Department of Food and Nutrition, Kunsan National University, Gunsan, Jeonbuk 54150, Republic of KoreaCorrespondence: Miae DooDepartment of Food and Nutrition, Kunsan National University, Daehak-Ro 558, Gunsan, Jeonbuk 54150, Republic of KoreaTel +82-63-469-4635Fax +82-63-469-2085Email miae_doo@kunsan.ac.krBackground and Objectives: To assess whether the consumption of dietary macronutrient could change metabolic syndrome (MetS) related to vitamin D deficiency according to menopausal status.Methods and Study Design: In a cross-sectional study of 8326 Korean women from the Korean National Health and Nutrition Examination Survey V (2010– 2012), we investigated the combined interaction effect of serum 25-hydroxyvitamin D [25(OH)D] concentration and menopausal status on MetS-related variables.Results: The prevalence rates of 25(OH)D deficiency (vitamin D < 50 nmol/L) among premenopausal and postmenopausal women were 84.5% and 67.9%, respectively. Significant differences in MetS-related variables such as body mass index (P< 0.001), waist circumference (P=0.005), fast glucose (P=0.048), triglycerides (P=0.001), and high-density lipoprotein cholesterol (P=0.027) based on 25(OH)D concentration were observed among postmenopausal women but not among premenopausal women. Among the postmenopausal women with high consumption of dietary carbohydrate, the adjusted odds ratios (ORs) [95% confidence intervals (95% CIs)] of MetS among participants with 25(OH)D deficiency increased 1.380-fold (95% CI = 1.086– 1.753) using the 25(OH)D-sufficient group as a reference. In contrast, the participants with 25(OH)D deficiency showed an increased risk of MetS [OR (95% CI) = 1.313 (1.041– 1.655)] with low-fat consumption. However, the aforementioned findings did not differ among premenopausal women.Conclusion: Thus, MetS due to 25(OH)D deficiency among postmenopausal women may be modified by the consumption of dietary macronutrient.Keywords: dietary macronutrient, Korean national health and nutrition examination survey, menopausal status, metabolic syndrome, vitamin D |
| first_indexed | 2024-04-10T18:39:06Z |
| format | Article |
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| institution | Directory Open Access Journal |
| issn | 1178-7007 |
| language | English |
| last_indexed | 2024-04-10T18:39:06Z |
| publishDate | 2020-10-01 |
| publisher | Dove Medical Press |
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| series | Diabetes, Metabolic Syndrome and Obesity |
| spelling | doaj.art-f0aadbe00a7347c5b50611543fade4132023-02-02T00:16:06ZengDove Medical PressDiabetes, Metabolic Syndrome and Obesity1178-70072020-10-01Volume 133601360957939Differences in the Association Among the Vitamin D Concentration, Dietary Macronutrient Consumption, and Metabolic Syndrome Depending on Pre- and Postmenopausal Status in Korean Women: A Cross-Sectional StudyChun HKim GDDoo MHyejin Chun,1 Gi Dae Kim,2 Miae Doo3 1Department of Family Medicine, CHA Bundang Medical Center, CHA University, Seongnam, Gyeonggi, 13496, Republic of Korea; 2Department of Food and Nutrition, Kyungnam University, Changwon, Gyeongnam 51767, Republic of Korea; 3Department of Food and Nutrition, Kunsan National University, Gunsan, Jeonbuk 54150, Republic of KoreaCorrespondence: Miae DooDepartment of Food and Nutrition, Kunsan National University, Daehak-Ro 558, Gunsan, Jeonbuk 54150, Republic of KoreaTel +82-63-469-4635Fax +82-63-469-2085Email miae_doo@kunsan.ac.krBackground and Objectives: To assess whether the consumption of dietary macronutrient could change metabolic syndrome (MetS) related to vitamin D deficiency according to menopausal status.Methods and Study Design: In a cross-sectional study of 8326 Korean women from the Korean National Health and Nutrition Examination Survey V (2010– 2012), we investigated the combined interaction effect of serum 25-hydroxyvitamin D [25(OH)D] concentration and menopausal status on MetS-related variables.Results: The prevalence rates of 25(OH)D deficiency (vitamin D < 50 nmol/L) among premenopausal and postmenopausal women were 84.5% and 67.9%, respectively. Significant differences in MetS-related variables such as body mass index (P< 0.001), waist circumference (P=0.005), fast glucose (P=0.048), triglycerides (P=0.001), and high-density lipoprotein cholesterol (P=0.027) based on 25(OH)D concentration were observed among postmenopausal women but not among premenopausal women. Among the postmenopausal women with high consumption of dietary carbohydrate, the adjusted odds ratios (ORs) [95% confidence intervals (95% CIs)] of MetS among participants with 25(OH)D deficiency increased 1.380-fold (95% CI = 1.086– 1.753) using the 25(OH)D-sufficient group as a reference. In contrast, the participants with 25(OH)D deficiency showed an increased risk of MetS [OR (95% CI) = 1.313 (1.041– 1.655)] with low-fat consumption. However, the aforementioned findings did not differ among premenopausal women.Conclusion: Thus, MetS due to 25(OH)D deficiency among postmenopausal women may be modified by the consumption of dietary macronutrient.Keywords: dietary macronutrient, Korean national health and nutrition examination survey, menopausal status, metabolic syndrome, vitamin Dhttps://www.dovepress.com/differences-in-the-association-among-the-vitamin-d-concentration-dieta-peer-reviewed-article-DMSOdietary macronutrientkorean national health and nutrition examination surveymenopausal statusmetabolic syndromevitamin d |
| spellingShingle | Chun H Kim GD Doo M Differences in the Association Among the Vitamin D Concentration, Dietary Macronutrient Consumption, and Metabolic Syndrome Depending on Pre- and Postmenopausal Status in Korean Women: A Cross-Sectional Study Diabetes, Metabolic Syndrome and Obesity dietary macronutrient korean national health and nutrition examination survey menopausal status metabolic syndrome vitamin d |
| title | Differences in the Association Among the Vitamin D Concentration, Dietary Macronutrient Consumption, and Metabolic Syndrome Depending on Pre- and Postmenopausal Status in Korean Women: A Cross-Sectional Study |
| title_full | Differences in the Association Among the Vitamin D Concentration, Dietary Macronutrient Consumption, and Metabolic Syndrome Depending on Pre- and Postmenopausal Status in Korean Women: A Cross-Sectional Study |
| title_fullStr | Differences in the Association Among the Vitamin D Concentration, Dietary Macronutrient Consumption, and Metabolic Syndrome Depending on Pre- and Postmenopausal Status in Korean Women: A Cross-Sectional Study |
| title_full_unstemmed | Differences in the Association Among the Vitamin D Concentration, Dietary Macronutrient Consumption, and Metabolic Syndrome Depending on Pre- and Postmenopausal Status in Korean Women: A Cross-Sectional Study |
| title_short | Differences in the Association Among the Vitamin D Concentration, Dietary Macronutrient Consumption, and Metabolic Syndrome Depending on Pre- and Postmenopausal Status in Korean Women: A Cross-Sectional Study |
| title_sort | differences in the association among the vitamin d concentration dietary macronutrient consumption and metabolic syndrome depending on pre and postmenopausal status in korean women a cross sectional study |
| topic | dietary macronutrient korean national health and nutrition examination survey menopausal status metabolic syndrome vitamin d |
| url | https://www.dovepress.com/differences-in-the-association-among-the-vitamin-d-concentration-dieta-peer-reviewed-article-DMSO |
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