Flavonoic content and antibacterial evaluation of Moringa oleifera Lam. leaves grow in Algeria
The objective of this study is to fight against antibiotic resistance, especially in urinary tract infection. To limit the spread of this scourge, we have proposed the use of flavonoid extract of the medicinal plant Moringa oleifera Lam against pathogenic bacteria of urinary tract infections. M. ole...
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wolters Kluwer Medknow Publications
2023-01-01
|
| Series: | Journal of Advanced Pharmaceutical Technology & Research |
| Subjects: | |
| Online Access: | http://www.japtr.org/article.asp?issn=2231-4040;year=2023;volume=14;issue=3;spage=191;epage=195;aulast=Boumaza-Hamladji |
| _version_ | 1797738697775382528 |
|---|---|
| author | Sarah Boumaza-Hamladji Narimen Benhabyles Souheyla Toubal Djillali El Haddad Ouahiba Bouchenak Nerdjes Bellalemi Drifa Berrichi Ibtissem Meziani |
| author_facet | Sarah Boumaza-Hamladji Narimen Benhabyles Souheyla Toubal Djillali El Haddad Ouahiba Bouchenak Nerdjes Bellalemi Drifa Berrichi Ibtissem Meziani |
| author_sort | Sarah Boumaza-Hamladji |
| collection | DOAJ |
| description | The objective of this study is to fight against antibiotic resistance, especially in urinary tract infection. To limit the spread of this scourge, we have proposed the use of flavonoid extract of the medicinal plant Moringa oleifera Lam against pathogenic bacteria of urinary tract infections. M. oleifera, was introduced in the arid regions of the Algerian Sahara for sustainable rural development in Algeria. The phytochemical study, revealed the presence of a multitude of metabolites. The yield of aqueous extract is 27.35% ± 1.95 and flavonoid concentration is 38.59 ± 0.002 mg EQ/gE. The high-performance liquid chromatography revealed the presence of 47 compounds, the most important of which are ascorbic acid (16.82%) and luteolin-7-Glycoside (26.8%). The aqueous extract has very significant antibacterial activity with an inhibition zone varying between 26.2 ± 0.25 (mm) for Bacillus anthracis and 12.66 ± 1.15 for Salmonella enteritidis. |
| first_indexed | 2024-03-12T13:46:36Z |
| format | Article |
| id | doaj.art-f0ab398ac02d4b8db602d4c835c7a0b2 |
| institution | Directory Open Access Journal |
| issn | 2231-4040 0976-2094 |
| language | English |
| last_indexed | 2024-03-12T13:46:36Z |
| publishDate | 2023-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Journal of Advanced Pharmaceutical Technology & Research |
| spelling | doaj.art-f0ab398ac02d4b8db602d4c835c7a0b22023-08-23T08:57:25ZengWolters Kluwer Medknow PublicationsJournal of Advanced Pharmaceutical Technology & Research2231-40400976-20942023-01-0114319119510.4103/JAPTR.JAPTR_126_23Flavonoic content and antibacterial evaluation of Moringa oleifera Lam. leaves grow in AlgeriaSarah Boumaza-HamladjiNarimen BenhabylesSouheyla ToubalDjillali El HaddadOuahiba BouchenakNerdjes BellalemiDrifa BerrichiIbtissem MezianiThe objective of this study is to fight against antibiotic resistance, especially in urinary tract infection. To limit the spread of this scourge, we have proposed the use of flavonoid extract of the medicinal plant Moringa oleifera Lam against pathogenic bacteria of urinary tract infections. M. oleifera, was introduced in the arid regions of the Algerian Sahara for sustainable rural development in Algeria. The phytochemical study, revealed the presence of a multitude of metabolites. The yield of aqueous extract is 27.35% ± 1.95 and flavonoid concentration is 38.59 ± 0.002 mg EQ/gE. The high-performance liquid chromatography revealed the presence of 47 compounds, the most important of which are ascorbic acid (16.82%) and luteolin-7-Glycoside (26.8%). The aqueous extract has very significant antibacterial activity with an inhibition zone varying between 26.2 ± 0.25 (mm) for Bacillus anthracis and 12.66 ± 1.15 for Salmonella enteritidis.http://www.japtr.org/article.asp?issn=2231-4040;year=2023;volume=14;issue=3;spage=191;epage=195;aulast=Boumaza-Hamladjiantibacterial activityflavonoidshigh-performance liquid chromatographymoringa oleifera lamurinary tract infection |
| spellingShingle | Sarah Boumaza-Hamladji Narimen Benhabyles Souheyla Toubal Djillali El Haddad Ouahiba Bouchenak Nerdjes Bellalemi Drifa Berrichi Ibtissem Meziani Flavonoic content and antibacterial evaluation of Moringa oleifera Lam. leaves grow in Algeria Journal of Advanced Pharmaceutical Technology & Research antibacterial activity flavonoids high-performance liquid chromatography moringa oleifera lam urinary tract infection |
| title | Flavonoic content and antibacterial evaluation of Moringa oleifera Lam. leaves grow in Algeria |
| title_full | Flavonoic content and antibacterial evaluation of Moringa oleifera Lam. leaves grow in Algeria |
| title_fullStr | Flavonoic content and antibacterial evaluation of Moringa oleifera Lam. leaves grow in Algeria |
| title_full_unstemmed | Flavonoic content and antibacterial evaluation of Moringa oleifera Lam. leaves grow in Algeria |
| title_short | Flavonoic content and antibacterial evaluation of Moringa oleifera Lam. leaves grow in Algeria |
| title_sort | flavonoic content and antibacterial evaluation of moringa oleifera lam leaves grow in algeria |
| topic | antibacterial activity flavonoids high-performance liquid chromatography moringa oleifera lam urinary tract infection |
| url | http://www.japtr.org/article.asp?issn=2231-4040;year=2023;volume=14;issue=3;spage=191;epage=195;aulast=Boumaza-Hamladji |
| work_keys_str_mv | AT sarahboumazahamladji flavonoiccontentandantibacterialevaluationofmoringaoleiferalamleavesgrowinalgeria AT narimenbenhabyles flavonoiccontentandantibacterialevaluationofmoringaoleiferalamleavesgrowinalgeria AT souheylatoubal flavonoiccontentandantibacterialevaluationofmoringaoleiferalamleavesgrowinalgeria AT djillalielhaddad flavonoiccontentandantibacterialevaluationofmoringaoleiferalamleavesgrowinalgeria AT ouahibabouchenak flavonoiccontentandantibacterialevaluationofmoringaoleiferalamleavesgrowinalgeria AT nerdjesbellalemi flavonoiccontentandantibacterialevaluationofmoringaoleiferalamleavesgrowinalgeria AT drifaberrichi flavonoiccontentandantibacterialevaluationofmoringaoleiferalamleavesgrowinalgeria AT ibtissemmeziani flavonoiccontentandantibacterialevaluationofmoringaoleiferalamleavesgrowinalgeria |