Cytokine Release Syndrome in the Immunotherapy of Hematological Malignancies: The Biology behind and Possible Clinical Consequences
Cytokine release syndrome (CRS) is an acute systemic inflammatory syndrome characterized by fever and multiple organ dysfunction associated with (i) chimeric antigen receptor (CAR)-T cell therapy, (ii) therapeutic antibodies, and (iii) haploidentical allogeneic stem cell transplantation (haplo-allo-...
Main Authors: | Tor Henrik Anderson Tvedt, Anh Khoi Vo, Øystein Bruserud, Håkon Reikvam |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2021-11-01
|
Series: | Journal of Clinical Medicine |
Subjects: | |
Online Access: | https://www.mdpi.com/2077-0383/10/21/5190 |
Similar Items
-
Haploidentical Hematopoietic Stem Cell Transplantation Followed by ‘Post-Cyclophosphamide’: The Future of Allogeneic Stem Cell Transplant
by: Samuel Cytryn, et al.
Published: (2020-04-01) -
Allogeneic gamma delta T cells as adoptive cellular therapy for hematologic malignancies
by: Navdeep Jhita, et al.
Published: (2022-06-01) -
Therapeutic Use of Valproic Acid and All-Trans Retinoic Acid in Acute Myeloid Leukemia—Literature Review and Discussion of Possible Use in Relapse after Allogeneic Stem Cell Transplantation
by: Øystein Bruserud, et al.
Published: (2021-05-01) -
Haploidentical CD19/CD22 bispecific CAR-T cells induced MRD-negative remission in a patient with relapsed and refractory adult B-ALL after haploidentical hematopoietic stem cell transplantation
by: Hejin Jia, et al.
Published: (2019-06-01) -
Graft Engineering and Adoptive Immunotherapy: New Approaches to Promote Immune Tolerance After Hematopoietic Stem Cell Transplantation
by: Alice Bertaina, et al.
Published: (2019-07-01)