Characterising the Response of Human Breast Cancer Cells to Polyamine Modulation

Characterising the Response of Human Breast Cancer Cells to Polyamine Modulation

Breast cancer is a complex heterogeneous disease with multiple underlying causes. The polyamines putrescine, spermidine, and spermine are polycationic molecules essential for cell proliferation. Their biosynthesis is upregulated in breast cancer and they contribute to disease progression. While elev...

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Bibliographic Details
Main Authors: Oluwaseun Akinyele, Heather M. Wallace
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Biomolecules
Subjects:
polyamines
cell growth
breast cancer subtypes
DFMO
Online Access:https://www.mdpi.com/2218-273X/11/5/743

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