Diverse Roles of Cellular Senescence in Skeletal Muscle Inflammation, Regeneration, and Therapeutics

Diverse Roles of Cellular Senescence in Skeletal Muscle Inflammation, Regeneration, and Therapeutics

Skeletal muscle undergoes vigorous tissue remodeling after injury. However, aging, chronic inflammatory diseases, sarcopenia, and neuromuscular disorders cause muscle loss and degeneration, resulting in muscular dysfunction. Cellular senescence, a state of irreversible cell cycle arrest, acts during...

Full description

Bibliographic Details
Main Authors: Yuki Saito, Takako S. Chikenji
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Pharmacology
Subjects:
senescence
skeletal muscle
chronic inflammation
aging
muscle regeneration
muscle stem cells
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.739510/full

Similar Items

Similar Items