Interactions between the apolipoprotein E ɛ4 allele status and adverse childhood experiences on depressive symptoms in older adults

Interactions between the apolipoprotein E ɛ4 allele status and adverse childhood experiences on depressive symptoms in older adults

Background: The influence of childhood adversity on depression is modulated by genetic vulnerability. The apolipoprotein E ɛ4 (APOE-ɛ4) allele is a strong genetic risk factor for Alzheimer's disease (AD). Because late-life depressive symptoms could be a part of the preclinical course of AD, the...

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Bibliographic Details
Main Authors: Subin Park, Yoon-Young Nam, Yoojin Sim, Jin Pyo Hong
Format: Article
Language:English
Published: Taylor & Francis Group 2015-01-01
Series:European Journal of Psychotraumatology
Subjects:
Depression
old age
APOE-ɛ4
childhood adversity
Online Access:http://www.ejpt.net/index.php/ejpt/article/view/25178/pdf_9

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