S-glutathionylation of Hsp90 enhances its degradation and correlates with favorable prognosis of breast cancer

S-glutathionylation of Hsp90 enhances its degradation and correlates with favorable prognosis of breast cancer

Heat shock protein 90 (Hsp90) is a ubiquitous chaperone to interact with numerous proteins to regulate multiple cellular processes, especially during cell proliferation and cell cycle progression. Hsp90 exists in a high level in tumor cells and tissues, and thus serves as a prognostic biomarker or t...

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Bibliographic Details
Main Authors: Yu-Yin Shih, Hsien-Ya Lin, Hau-Ming Jan, Yu-Ju Chen, Lih-Lih Ong, Alice Lin-Tsing Yu, Chun-Hung Lin
Format: Article
Language:English
Published: Elsevier 2022-11-01
Series:Redox Biology
Subjects:
S-glutathionylation
Hsp90
Breast cancer
Post-translational modification
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231722002737

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http://www.sciencedirect.com/science/article/pii/S2213231722002737

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