S-glutathionylation of Hsp90 enhances its degradation and correlates with favorable prognosis of breast cancer
Heat shock protein 90 (Hsp90) is a ubiquitous chaperone to interact with numerous proteins to regulate multiple cellular processes, especially during cell proliferation and cell cycle progression. Hsp90 exists in a high level in tumor cells and tissues, and thus serves as a prognostic biomarker or t...
Main Authors: | Yu-Yin Shih, Hsien-Ya Lin, Hau-Ming Jan, Yu-Ju Chen, Lih-Lih Ong, Alice Lin-Tsing Yu, Chun-Hung Lin |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2022-11-01
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Series: | Redox Biology |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2213231722002737 |
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