A Comprehensive Approach to Sequence-oriented IsomiR annotation (CASMIR): demonstration with IsomiR profiling in colorectal neoplasia

A Comprehensive Approach to Sequence-oriented IsomiR annotation (CASMIR): demonstration with IsomiR profiling in colorectal neoplasia

Abstract Background MicroRNA (miRNA) profiling is an important step in studying biological associations and identifying marker candidates. miRNA exists in isoforms, called isomiRs, which may exhibit distinct properties. With conventional profiling methods, limitations in assay and analysis platforms...

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Bibliographic Details
Main Authors: Chung Wah Wu, Jared M. Evans, Shengbing Huang, Douglas W. Mahoney, Brian A. Dukek, William R. Taylor, Tracy C. Yab, Thomas C. Smyrk, Jin Jen, John B. Kisiel, David A. Ahlquist
Format: Article
Language:English
Published: BMC 2018-05-01
Series:BMC Genomics
Subjects:
MicroRNAs
High-throughput nucleotide sequencing
Colorectal neoplasms
Gene expression profiling
Biomarkers
Online Access:http://link.springer.com/article/10.1186/s12864-018-4794-7

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