Exploring the Pathological Effect of Aβ42 Oligomers on Neural Networks in Primary Cortical Neuron Culture

Exploring the Pathological Effect of Aβ42 Oligomers on Neural Networks in Primary Cortical Neuron Culture

Alzheimer’s disease (AD) is a multifactorial disorder that affects cognitive functioning, behavior, and neuronal properties. The neuronal dysfunction is primarily responsible for cognitive decline in AD patients, with many causal factors including plaque accumulation of Aβ42. Neural hyperactivity in...

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Bibliographic Details
Main Authors: Dulguun Ganbat, Jae Kyong Jeon, Yunjong Lee, Sang Seong Kim
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:International Journal of Molecular Sciences
Subjects:
Alzheimer’s disease
Aβ42
oligomer
high-density multielectrode array
neuronal network
graph theory
Online Access:https://www.mdpi.com/1422-0067/24/7/6641

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