Maintained avalanche dynamics during task-induced changes of neuronal activity in nonhuman primates
Sensory events, cognitive processing and motor actions correlate with transient changes in neuronal activity. In cortex, these transients form widespread spatiotemporal patterns with largely unknown statistical regularities. Here, we show that activity associated with behavioral events carry the sig...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
eLife Sciences Publications Ltd
2017-11-01
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| Series: | eLife |
| Subjects: | |
| Online Access: | https://elifesciences.org/articles/27119 |
| _version_ | 1828222086789726208 |
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| author | Shan Yu Tiago L Ribeiro Christian Meisel Samantha Chou Andrew Mitz Richard Saunders Dietmar Plenz |
| author_facet | Shan Yu Tiago L Ribeiro Christian Meisel Samantha Chou Andrew Mitz Richard Saunders Dietmar Plenz |
| author_sort | Shan Yu |
| collection | DOAJ |
| description | Sensory events, cognitive processing and motor actions correlate with transient changes in neuronal activity. In cortex, these transients form widespread spatiotemporal patterns with largely unknown statistical regularities. Here, we show that activity associated with behavioral events carry the signature of scale-invariant spatiotemporal clusters, neuronal avalanches. Using high-density microelectrode arrays in nonhuman primates, we recorded extracellular unit activity and the local field potential (LFP) in premotor and prefrontal cortex during motor and cognitive tasks. Unit activity and negative LFP deflections (nLFP) consistently changed in rate at single electrodes during tasks. Accordingly, nLFP clusters on the array deviated from scale-invariance compared to ongoing activity. Scale-invariance was recovered using ‘adaptive binning’, that is identifying clusters at temporal resolution given by task-induced changes in nLFP rate. Measures of LFP synchronization confirmed and computer simulations detailed our findings. We suggest optimization principles identified for avalanches during ongoing activity to apply to cortical information processing during behavior. |
| first_indexed | 2024-04-12T16:49:23Z |
| format | Article |
| id | doaj.art-f0c06709a9e4442cbc1dad6c4f4ecc4f |
| institution | Directory Open Access Journal |
| issn | 2050-084X |
| language | English |
| last_indexed | 2024-04-12T16:49:23Z |
| publishDate | 2017-11-01 |
| publisher | eLife Sciences Publications Ltd |
| record_format | Article |
| series | eLife |
| spelling | doaj.art-f0c06709a9e4442cbc1dad6c4f4ecc4f2022-12-22T03:24:27ZengeLife Sciences Publications LtdeLife2050-084X2017-11-01610.7554/eLife.27119Maintained avalanche dynamics during task-induced changes of neuronal activity in nonhuman primatesShan Yu0https://orcid.org/0000-0002-9008-6658Tiago L Ribeiro1https://orcid.org/0000-0003-3195-9284Christian Meisel2Samantha Chou3Andrew Mitz4https://orcid.org/0000-0002-8045-0970Richard Saunders5Dietmar Plenz6https://orcid.org/0000-0002-0008-3657Section on Critical Brain Dynamics, National Institute of Mental Health, Bethesda, United StatesSection on Critical Brain Dynamics, National Institute of Mental Health, Bethesda, United StatesSection on Critical Brain Dynamics, National Institute of Mental Health, Bethesda, United StatesSection on Critical Brain Dynamics, National Institute of Mental Health, Bethesda, United StatesLaboratory of Neuropsychology, National Institute of Mental Health, Bethesda, United StatesLaboratory of Neuropsychology, National Institute of Mental Health, Bethesda, United StatesSection on Critical Brain Dynamics, National Institute of Mental Health, Bethesda, United StatesSensory events, cognitive processing and motor actions correlate with transient changes in neuronal activity. In cortex, these transients form widespread spatiotemporal patterns with largely unknown statistical regularities. Here, we show that activity associated with behavioral events carry the signature of scale-invariant spatiotemporal clusters, neuronal avalanches. Using high-density microelectrode arrays in nonhuman primates, we recorded extracellular unit activity and the local field potential (LFP) in premotor and prefrontal cortex during motor and cognitive tasks. Unit activity and negative LFP deflections (nLFP) consistently changed in rate at single electrodes during tasks. Accordingly, nLFP clusters on the array deviated from scale-invariance compared to ongoing activity. Scale-invariance was recovered using ‘adaptive binning’, that is identifying clusters at temporal resolution given by task-induced changes in nLFP rate. Measures of LFP synchronization confirmed and computer simulations detailed our findings. We suggest optimization principles identified for avalanches during ongoing activity to apply to cortical information processing during behavior.https://elifesciences.org/articles/27119cortexprefrontalpremotorbehaviorneuronal avalancheslocal-field potential |
| spellingShingle | Shan Yu Tiago L Ribeiro Christian Meisel Samantha Chou Andrew Mitz Richard Saunders Dietmar Plenz Maintained avalanche dynamics during task-induced changes of neuronal activity in nonhuman primates eLife cortex prefrontal premotor behavior neuronal avalanches local-field potential |
| title | Maintained avalanche dynamics during task-induced changes of neuronal activity in nonhuman primates |
| title_full | Maintained avalanche dynamics during task-induced changes of neuronal activity in nonhuman primates |
| title_fullStr | Maintained avalanche dynamics during task-induced changes of neuronal activity in nonhuman primates |
| title_full_unstemmed | Maintained avalanche dynamics during task-induced changes of neuronal activity in nonhuman primates |
| title_short | Maintained avalanche dynamics during task-induced changes of neuronal activity in nonhuman primates |
| title_sort | maintained avalanche dynamics during task induced changes of neuronal activity in nonhuman primates |
| topic | cortex prefrontal premotor behavior neuronal avalanches local-field potential |
| url | https://elifesciences.org/articles/27119 |
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