Acute pulmonary histoplasmosis related to occupational roofing: A case report of two brothers

Background and Purpose: Histoplasma capsulatum is the cause of a prevalent fungal disease in certain regions in the United States of America, like Ohio and the Mississippi River. Its clinical manifestations range from asymptomatic to life-threatening diseases,according to the immune system. A defini...

Full description

Bibliographic Details
Main Authors: Martin Gnoni, Timothy McCann, Adrian Riva-Moscoso, Fortunato Príncipe-Meneses, Diego Chambergo-Michilot
Format: Article
Language:English
Published: Mazandaran University of Medical Sciences 2021-12-01
Series:Current Medical Mycology
Subjects:
Online Access:http://cmm.mazums.ac.ir/article_139758_01be00210bd77ba588675d0d5f1832a6.pdf
_version_ 1797973886949654528
author Martin Gnoni
Timothy McCann
Adrian Riva-Moscoso
Fortunato Príncipe-Meneses
Diego Chambergo-Michilot
author_facet Martin Gnoni
Timothy McCann
Adrian Riva-Moscoso
Fortunato Príncipe-Meneses
Diego Chambergo-Michilot
author_sort Martin Gnoni
collection DOAJ
description Background and Purpose: Histoplasma capsulatum is the cause of a prevalent fungal disease in certain regions in the United States of America, like Ohio and the Mississippi River. Its clinical manifestations range from asymptomatic to life-threatening diseases,according to the immune system. A definitive diagnosis is made by biopsy.Case report: Two middle-aged brothers presented with a nine-day history of severe progressive dyspnea. Both were living in Cincinnati, Ohio, and encountered bird droppings 7 days prior to symptoms while working on a roofing project. It should be mentioned that they were not wearing masks. After extensive testing, they were diagnosed with acute pulmonary histoplasmosis. Both were successfully treated with azole-derivative fungal therapy.Conclusion: This is the first case of histoplasmosis acquired through occupational exposure related to roofing and is unique given the two patients were siblings
first_indexed 2024-04-11T04:11:19Z
format Article
id doaj.art-f0c63ed5e38f4ff497ef8335934244d2
institution Directory Open Access Journal
issn 2423-3439
2423-3420
language English
last_indexed 2024-04-11T04:11:19Z
publishDate 2021-12-01
publisher Mazandaran University of Medical Sciences
record_format Article
series Current Medical Mycology
spelling doaj.art-f0c63ed5e38f4ff497ef8335934244d22023-01-01T06:33:11ZengMazandaran University of Medical SciencesCurrent Medical Mycology2423-34392423-34202021-12-0174343710.18502/cmm.7.4.8409139758Acute pulmonary histoplasmosis related to occupational roofing: A case report of two brothersMartin Gnoni0Timothy McCann1Adrian Riva-Moscoso2Fortunato Príncipe-Meneses3Diego Chambergo-Michilot4Department of Internal Medicine, Good Samaritan Hospital, Cincinnati, Ohio, United States of AmericaTrihealth Internal Medicine, Infectious Diseases, Cincinnati, Ohio, United States of AmericaSchool of Medicine, Peruvian University of Applied Sciences, Lima, PeruSchool of Medicine, Peruvian University of Applied Sciences, Lima, PeruSchool of Medicine, Scientific University of the South, Lima, PeruBackground and Purpose: Histoplasma capsulatum is the cause of a prevalent fungal disease in certain regions in the United States of America, like Ohio and the Mississippi River. Its clinical manifestations range from asymptomatic to life-threatening diseases,according to the immune system. A definitive diagnosis is made by biopsy.Case report: Two middle-aged brothers presented with a nine-day history of severe progressive dyspnea. Both were living in Cincinnati, Ohio, and encountered bird droppings 7 days prior to symptoms while working on a roofing project. It should be mentioned that they were not wearing masks. After extensive testing, they were diagnosed with acute pulmonary histoplasmosis. Both were successfully treated with azole-derivative fungal therapy.Conclusion: This is the first case of histoplasmosis acquired through occupational exposure related to roofing and is unique given the two patients were siblingshttp://cmm.mazums.ac.ir/article_139758_01be00210bd77ba588675d0d5f1832a6.pdffungalhistoplasmosisohiosporesunited states
spellingShingle Martin Gnoni
Timothy McCann
Adrian Riva-Moscoso
Fortunato Príncipe-Meneses
Diego Chambergo-Michilot
Acute pulmonary histoplasmosis related to occupational roofing: A case report of two brothers
Current Medical Mycology
fungal
histoplasmosis
ohio
spores
united states
title Acute pulmonary histoplasmosis related to occupational roofing: A case report of two brothers
title_full Acute pulmonary histoplasmosis related to occupational roofing: A case report of two brothers
title_fullStr Acute pulmonary histoplasmosis related to occupational roofing: A case report of two brothers
title_full_unstemmed Acute pulmonary histoplasmosis related to occupational roofing: A case report of two brothers
title_short Acute pulmonary histoplasmosis related to occupational roofing: A case report of two brothers
title_sort acute pulmonary histoplasmosis related to occupational roofing a case report of two brothers
topic fungal
histoplasmosis
ohio
spores
united states
url http://cmm.mazums.ac.ir/article_139758_01be00210bd77ba588675d0d5f1832a6.pdf
work_keys_str_mv AT martingnoni acutepulmonaryhistoplasmosisrelatedtooccupationalroofingacasereportoftwobrothers
AT timothymccann acutepulmonaryhistoplasmosisrelatedtooccupationalroofingacasereportoftwobrothers
AT adrianrivamoscoso acutepulmonaryhistoplasmosisrelatedtooccupationalroofingacasereportoftwobrothers
AT fortunatoprincipemeneses acutepulmonaryhistoplasmosisrelatedtooccupationalroofingacasereportoftwobrothers
AT diegochambergomichilot acutepulmonaryhistoplasmosisrelatedtooccupationalroofingacasereportoftwobrothers