Truncation of Lipopolysaccharide Core Decreases <i>Yersinia pestis</i> Virulence

Truncation of Lipopolysaccharide Core Decreases <i>Yersinia pestis</i> Virulence

The isogenic set of Yersinia pestis strains including wild-type strain 231 and its mutants with deletions of the structural genes, wabD, waaL, waaQ, waaE, and hldE, responsible for core oligosaccharide synthesis was generated using site directed mutagenesis. It was shown that gradual decrease of the...

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Bibliographic Details
Main Authors: S. V. Dentovskaya, M. E. Platonov, T. I. Kombarova, G. M. Titareva, I. V. Bakhteeva, R. Z. Shaikhutdinova, S. A. Ivanov, A. P. Anisimov
Format: Article
Language:Russian
Published: Federal Government Health Institution, Russian Research Anti-Plague Institute “Microbe” 2009-02-01
Series:Проблемы особо опасных инфекций
Subjects:
plague agent
lps
core
virulence
Online Access:https://journal.microbe.ru/jour/article/view/1002

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