Histopathological Spectrum of Male Genital System Tumours in a Tertiary Care Hospital Faridkot, Punjab
Introduction: The male genital system consists of the prostate, seminal vesicle, testes, epididymis, vas deferens, bulbourethral gland, ejaculatory duct, penis and scrotum. Male genital cancers are histologically diverse. They are difficult to detect and treat because of their anatomic locations...
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| Format: | Article |
| Language: | English |
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JCDR Research and Publications Private Limited
2021-09-01
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| Series: | Journal of Clinical and Diagnostic Research |
| Subjects: | |
| Online Access: | https://www.jcdr.net/articles/PDF/15418/49233_CE[Ra1]_F[SH]_PF1(SC_AnK)_PFA(AnK)_PB(SC_AnK)_PN(SS).pdf |
| _version_ | 1818917262534377472 |
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| author | Aradhana Singh Hada Sarita Nibhori Vaneet Kaur Sandhu Nitin Nagpal |
| author_facet | Aradhana Singh Hada Sarita Nibhori Vaneet Kaur Sandhu Nitin Nagpal |
| author_sort | Aradhana Singh Hada |
| collection | DOAJ |
| description | Introduction: The male genital system consists of the prostate,
seminal vesicle, testes, epididymis, vas deferens, bulbourethral
gland, ejaculatory duct, penis and scrotum. Male genital cancers
are histologically diverse. They are difficult to detect and treat
because of their anatomic locations, biological characters and
complications.
Aim: To study the histopathological spectrum of tumours of the
male genital system according to World Health Organisation (WHO)
classification.
Materials and Methods: The present study is a hospital based
descriptive study conducted in the Department of Pathology,
Guru Gobind Singh Medical College and Hospital, Faridkot,
Punjab, India, during February 2019 to August 2020 which
included 128 cases. All biopsies, specimens and review blocks
and slides of male genital tract tumours were processed and
slides were stained with Haematoxylin and Eosin (H&E) stain.
Serum tumour markers and immunohistochemical stains were
used. The clinical information including symptoms related to the
male genital system, histopathological findings and diagnosis
were recorded on the predesigned proforma. Other necessary
information was collected from the requisition form received
along with the biopsy material. The association between categorical
variables was explored using Pearson’s Chi-square test. A p-value
<0.05 was considered statistically significant for this study.
Results: The present study included 128 cases, of which the majority
of the cases 82 cases (64%) were that of prostate, 28 cases (21.9%)
of the penis, 15 cases (11.7%) of testes, two cases (1.6%) were
that of the scrotum and one case (0.8%) was of the epididymis.
The histopathological spectrum showed adenocarcinoma was
present in 80 (62.5%), leiomyosarcoma in 01 (0.8%), lymphoma in
01 (0.8%), mixed germ cell tumour in 9 (7%), seminoma in 5 (3.9%),
postpubertal teratoma in 1 (0.8%), basaloid in 1 (0.8%), papillarybasaloid in 2 (1.6%).
Conclusion: Prostate tumours outnumbered all other tumours of
the male genital tract with adenocarcinoma of prostate followed
by squamous cell carcinoma of the penis and mixed Germ Cell
Tumour (GCT) of testes. The present study provides updated
information regarding the histopathological spectrum of male
genital system tumours. |
| first_indexed | 2024-12-20T00:31:16Z |
| format | Article |
| id | doaj.art-f0c895c8221241958b3828b07809caa7 |
| institution | Directory Open Access Journal |
| issn | 2249-782X 0973-709X |
| language | English |
| last_indexed | 2024-12-20T00:31:16Z |
| publishDate | 2021-09-01 |
| publisher | JCDR Research and Publications Private Limited |
| record_format | Article |
| series | Journal of Clinical and Diagnostic Research |
| spelling | doaj.art-f0c895c8221241958b3828b07809caa72022-12-21T19:59:56ZengJCDR Research and Publications Private LimitedJournal of Clinical and Diagnostic Research2249-782X0973-709X2021-09-01159EC24EC2810.7860/JCDR/2021/49233.15418Histopathological Spectrum of Male Genital System Tumours in a Tertiary Care Hospital Faridkot, PunjabAradhana Singh Hada0Sarita Nibhori1Vaneet Kaur SandhuNitin NagpalJunior Resident, Department of Pathology, Guru Gobind Singh Medical College and Hospital, Faridkot, Punjab, India.Professor and Head, Department of Pathology, Guru Gobind Singh Medical College and Hospital, Faridkot, Punjab, India.Introduction: The male genital system consists of the prostate, seminal vesicle, testes, epididymis, vas deferens, bulbourethral gland, ejaculatory duct, penis and scrotum. Male genital cancers are histologically diverse. They are difficult to detect and treat because of their anatomic locations, biological characters and complications. Aim: To study the histopathological spectrum of tumours of the male genital system according to World Health Organisation (WHO) classification. Materials and Methods: The present study is a hospital based descriptive study conducted in the Department of Pathology, Guru Gobind Singh Medical College and Hospital, Faridkot, Punjab, India, during February 2019 to August 2020 which included 128 cases. All biopsies, specimens and review blocks and slides of male genital tract tumours were processed and slides were stained with Haematoxylin and Eosin (H&E) stain. Serum tumour markers and immunohistochemical stains were used. The clinical information including symptoms related to the male genital system, histopathological findings and diagnosis were recorded on the predesigned proforma. Other necessary information was collected from the requisition form received along with the biopsy material. The association between categorical variables was explored using Pearson’s Chi-square test. A p-value <0.05 was considered statistically significant for this study. Results: The present study included 128 cases, of which the majority of the cases 82 cases (64%) were that of prostate, 28 cases (21.9%) of the penis, 15 cases (11.7%) of testes, two cases (1.6%) were that of the scrotum and one case (0.8%) was of the epididymis. The histopathological spectrum showed adenocarcinoma was present in 80 (62.5%), leiomyosarcoma in 01 (0.8%), lymphoma in 01 (0.8%), mixed germ cell tumour in 9 (7%), seminoma in 5 (3.9%), postpubertal teratoma in 1 (0.8%), basaloid in 1 (0.8%), papillarybasaloid in 2 (1.6%). Conclusion: Prostate tumours outnumbered all other tumours of the male genital tract with adenocarcinoma of prostate followed by squamous cell carcinoma of the penis and mixed Germ Cell Tumour (GCT) of testes. The present study provides updated information regarding the histopathological spectrum of male genital system tumours.https://www.jcdr.net/articles/PDF/15418/49233_CE[Ra1]_F[SH]_PF1(SC_AnK)_PFA(AnK)_PB(SC_AnK)_PN(SS).pdfadenocarcinomamixed germ cell tumourspenisscrotumseminomas |
| spellingShingle | Aradhana Singh Hada Sarita Nibhori Vaneet Kaur Sandhu Nitin Nagpal Histopathological Spectrum of Male Genital System Tumours in a Tertiary Care Hospital Faridkot, Punjab Journal of Clinical and Diagnostic Research adenocarcinoma mixed germ cell tumours penis scrotum seminomas |
| title | Histopathological Spectrum of Male Genital System Tumours in a Tertiary Care Hospital Faridkot, Punjab |
| title_full | Histopathological Spectrum of Male Genital System Tumours in a Tertiary Care Hospital Faridkot, Punjab |
| title_fullStr | Histopathological Spectrum of Male Genital System Tumours in a Tertiary Care Hospital Faridkot, Punjab |
| title_full_unstemmed | Histopathological Spectrum of Male Genital System Tumours in a Tertiary Care Hospital Faridkot, Punjab |
| title_short | Histopathological Spectrum of Male Genital System Tumours in a Tertiary Care Hospital Faridkot, Punjab |
| title_sort | histopathological spectrum of male genital system tumours in a tertiary care hospital faridkot punjab |
| topic | adenocarcinoma mixed germ cell tumours penis scrotum seminomas |
| url | https://www.jcdr.net/articles/PDF/15418/49233_CE[Ra1]_F[SH]_PF1(SC_AnK)_PFA(AnK)_PB(SC_AnK)_PN(SS).pdf |
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