In-silico EEG biomarkers of reduced inhibition in human cortical microcircuits in depression

In-silico EEG biomarkers of reduced inhibition in human cortical microcircuits in depression

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Reduced cortical inhibition by somatostatin-expressing (SST) interneurons has been strongly associated with treatment-resistant depression. However, due to technical limitations it is impossible to establish experimentally in humans whether the effects of reduced SST interneuron inhibition on microc...

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Bibliographic Details
Main Authors: Frank Mazza, Alexandre Guet-McCreight, Taufik A. Valiante, John D. Griffiths, Etay Hay
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-04-01
Series:PLoS Computational Biology
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10085061/?tool=EBI

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