Concomitant Presence of Carcinoma of Breast in a Patient with Early-Onset Cataract: First Case Report of a Potential Association
A recent nation-wide population based retrospective cohort study from Taiwan in 2014 suggested a propensity of developing breast cancer in young females with early-onset cataract. We report here a case of a young non-obese female who presented to us with a large lump in the right breast with skin...
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
JCDR Research and Publications Private Limited
2017-05-01
|
| Series: | Journal of Clinical and Diagnostic Research |
| Subjects: | |
| Online Access: | https://jcdr.net/articles/PDF/9894/26913_CE[Ra]_F(Sh)_PF1(PG_SS)_PFA(PG_SS).pdf |
| _version_ | 1818190592552730624 |
|---|---|
| author | Shahbaz Habib Faridi Kaushal Deep Singh Mehershree Lodhi |
| author_facet | Shahbaz Habib Faridi Kaushal Deep Singh Mehershree Lodhi |
| author_sort | Shahbaz Habib Faridi |
| collection | DOAJ |
| description | A recent nation-wide population based retrospective cohort study from Taiwan in 2014 suggested a propensity of developing breast
cancer in young females with early-onset cataract. We report here a case of a young non-obese female who presented to us with
a large lump in the right breast with skin nodules and bilateral painless progressive diminution of vision. Patient was diagnosed to
be suffering from locally advanced carcinoma of right breast with axillary metastasis (Stage III B) and bilateral early-onset nuclear
cataract. Patient was started on taxane and anthracycline based neoadjuvant chemotherapy and after three cycles of chemotherapy
patient showed partial response (≈50% reduction of tumour mass). Patient underwent small incision cataract surgery in left eye
after the first cycle of chemotherapy. However, the patient was lost before any operative intervention could be done as she died
in a road traffic accident. Possible mechanism of development of breast cancer in patients with early-onset cataract is discussed.
This is the first reported case of a patient of early–onset cataract developing breast cancer as well as the first reported case of
concomitant presence of early-onset bilateral cataract with breast cancer. |
| first_indexed | 2024-12-12T00:01:10Z |
| format | Article |
| id | doaj.art-f0cd726d35544f44a921798c63dd44ef |
| institution | Directory Open Access Journal |
| issn | 2249-782X 0973-709X |
| language | English |
| last_indexed | 2024-12-12T00:01:10Z |
| publishDate | 2017-05-01 |
| publisher | JCDR Research and Publications Private Limited |
| record_format | Article |
| series | Journal of Clinical and Diagnostic Research |
| spelling | doaj.art-f0cd726d35544f44a921798c63dd44ef2022-12-22T00:45:14ZengJCDR Research and Publications Private LimitedJournal of Clinical and Diagnostic Research2249-782X0973-709X2017-05-01115PD05PD0710.7860/JCDR/2017/26913.9894Concomitant Presence of Carcinoma of Breast in a Patient with Early-Onset Cataract: First Case Report of a Potential AssociationShahbaz Habib Faridi0Kaushal Deep Singh1Mehershree Lodhi2Assistant Professor, Department of Surgery, Jawaharlal Nehru Medical College, Aligarh Muslim University, Aligarh, Uttar Pradesh, India.Senior Resident, Department of Surgery, Jawaharlal Nehru Medical College, Aligarh Muslim University, Aligarh, Uttar Pradesh, India.Junior Resident, Department of Microbiology, King George Medical University, Lucknow, Uttar Pradesh, India.A recent nation-wide population based retrospective cohort study from Taiwan in 2014 suggested a propensity of developing breast cancer in young females with early-onset cataract. We report here a case of a young non-obese female who presented to us with a large lump in the right breast with skin nodules and bilateral painless progressive diminution of vision. Patient was diagnosed to be suffering from locally advanced carcinoma of right breast with axillary metastasis (Stage III B) and bilateral early-onset nuclear cataract. Patient was started on taxane and anthracycline based neoadjuvant chemotherapy and after three cycles of chemotherapy patient showed partial response (≈50% reduction of tumour mass). Patient underwent small incision cataract surgery in left eye after the first cycle of chemotherapy. However, the patient was lost before any operative intervention could be done as she died in a road traffic accident. Possible mechanism of development of breast cancer in patients with early-onset cataract is discussed. This is the first reported case of a patient of early–onset cataract developing breast cancer as well as the first reported case of concomitant presence of early-onset bilateral cataract with breast cancer.https://jcdr.net/articles/PDF/9894/26913_CE[Ra]_F(Sh)_PF1(PG_SS)_PFA(PG_SS).pdfadjuvant chemoradiationanthracyclineearly-onset cataractlocally advanced carcinoma breastmodified radical mastectomy |
| spellingShingle | Shahbaz Habib Faridi Kaushal Deep Singh Mehershree Lodhi Concomitant Presence of Carcinoma of Breast in a Patient with Early-Onset Cataract: First Case Report of a Potential Association Journal of Clinical and Diagnostic Research adjuvant chemoradiation anthracycline early-onset cataract locally advanced carcinoma breast modified radical mastectomy |
| title | Concomitant Presence of Carcinoma of Breast in a Patient with Early-Onset Cataract: First Case Report of a Potential Association |
| title_full | Concomitant Presence of Carcinoma of Breast in a Patient with Early-Onset Cataract: First Case Report of a Potential Association |
| title_fullStr | Concomitant Presence of Carcinoma of Breast in a Patient with Early-Onset Cataract: First Case Report of a Potential Association |
| title_full_unstemmed | Concomitant Presence of Carcinoma of Breast in a Patient with Early-Onset Cataract: First Case Report of a Potential Association |
| title_short | Concomitant Presence of Carcinoma of Breast in a Patient with Early-Onset Cataract: First Case Report of a Potential Association |
| title_sort | concomitant presence of carcinoma of breast in a patient with early onset cataract first case report of a potential association |
| topic | adjuvant chemoradiation anthracycline early-onset cataract locally advanced carcinoma breast modified radical mastectomy |
| url | https://jcdr.net/articles/PDF/9894/26913_CE[Ra]_F(Sh)_PF1(PG_SS)_PFA(PG_SS).pdf |
| work_keys_str_mv | AT shahbazhabibfaridi concomitantpresenceofcarcinomaofbreastinapatientwithearlyonsetcataractfirstcasereportofapotentialassociation AT kaushaldeepsingh concomitantpresenceofcarcinomaofbreastinapatientwithearlyonsetcataractfirstcasereportofapotentialassociation AT mehershreelodhi concomitantpresenceofcarcinomaofbreastinapatientwithearlyonsetcataractfirstcasereportofapotentialassociation |