Abnormal transcriptome-wide DNA demethylation induced by folate deficiency causes neural tube defects

Neural tube defect (NTDs) is one of the most common and serious fetal and neonatal birth defects. Neural tube closure (NTC) is an exquisitely coordinated process and this procedure is influenced by both genetic and environmental factor. Folic acid (FA) supplementation is an effective for prevention...

Full description

Bibliographic Details
Main Authors: Shan Wang, Yubing Zeng, Pei Pei, Xuejia He, Fan Liu, Ting Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Genetics
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2022.987210/full