Potential prognostic value of miR-132 and miR-212 expression in mCRPC patients

To the Editor, we have been very pleased to read the interesting work proposed by Salemi et al. regarding the expression of specific fragments of microRNA (miRNA), particularly miR-132 and miR-212, as potential key regulators in prostate cancer (PCa). As outlined by the Authors, the altered express...

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Main Authors: Mariano Pontico, Viviana Frantellizzi, Luca Cindolo, Giuseppe De Vincentis
Format: Article
Language:English
Published: PAGEPress Publications 2021-10-01
Series:Archivio Italiano di Urologia e Andrologia
Subjects:
Online Access:https://pagepressjournals.org/index.php/aiua/article/view/9499
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author Mariano Pontico
Viviana Frantellizzi
Luca Cindolo
Giuseppe De Vincentis
author_facet Mariano Pontico
Viviana Frantellizzi
Luca Cindolo
Giuseppe De Vincentis
author_sort Mariano Pontico
collection DOAJ
description To the Editor, we have been very pleased to read the interesting work proposed by Salemi et al. regarding the expression of specific fragments of microRNA (miRNA), particularly miR-132 and miR-212, as potential key regulators in prostate cancer (PCa). As outlined by the Authors, the altered expression of miRNAs in cancer pathogenesis represents a well-consolidated knowledge in the current literature. More specifically, both miR-212 and miR-132 regulate subsets of genes involved in tumor progression in several tumor cell types as PCa, proving a central role in tumorigenesis, cell adhesion, and angiogenesis. In addition, a strong association between miR-132 expression and high Gleason score PCa has been lately depicted [...].
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spelling doaj.art-f0d252d7b103486ca0fe3d5a8e449cd92022-12-21T17:16:21ZengPAGEPress PublicationsArchivio Italiano di Urologia e Andrologia1124-35622282-41972021-10-0193310.4081/aiua.2021.3.373Potential prognostic value of miR-132 and miR-212 expression in mCRPC patientsMariano Pontico0Viviana Frantellizzi1Luca Cindolo2Giuseppe De Vincentis3Program in Morphogenesis and Tissue Engineering, Department of Medico-Surgical Sciences and Biotechnologies, Sapienza University of RomeDepartment of Radiological Sciences, Oncology and Anatomical Pathology, Sapienza, “Sapienza” University of RomeDepartment of Urology, "Villa Stuart" Private Hospital, RomeDepartment of Radiological Sciences, Oncology and Anatomical Pathology, Sapienza, “Sapienza” University of RomeTo the Editor, we have been very pleased to read the interesting work proposed by Salemi et al. regarding the expression of specific fragments of microRNA (miRNA), particularly miR-132 and miR-212, as potential key regulators in prostate cancer (PCa). As outlined by the Authors, the altered expression of miRNAs in cancer pathogenesis represents a well-consolidated knowledge in the current literature. More specifically, both miR-212 and miR-132 regulate subsets of genes involved in tumor progression in several tumor cell types as PCa, proving a central role in tumorigenesis, cell adhesion, and angiogenesis. In addition, a strong association between miR-132 expression and high Gleason score PCa has been lately depicted [...].https://pagepressjournals.org/index.php/aiua/article/view/9499Letter to the editor
spellingShingle Mariano Pontico
Viviana Frantellizzi
Luca Cindolo
Giuseppe De Vincentis
Potential prognostic value of miR-132 and miR-212 expression in mCRPC patients
Archivio Italiano di Urologia e Andrologia
Letter to the editor
title Potential prognostic value of miR-132 and miR-212 expression in mCRPC patients
title_full Potential prognostic value of miR-132 and miR-212 expression in mCRPC patients
title_fullStr Potential prognostic value of miR-132 and miR-212 expression in mCRPC patients
title_full_unstemmed Potential prognostic value of miR-132 and miR-212 expression in mCRPC patients
title_short Potential prognostic value of miR-132 and miR-212 expression in mCRPC patients
title_sort potential prognostic value of mir 132 and mir 212 expression in mcrpc patients
topic Letter to the editor
url https://pagepressjournals.org/index.php/aiua/article/view/9499
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