Potential prognostic value of miR-132 and miR-212 expression in mCRPC patients
To the Editor, we have been very pleased to read the interesting work proposed by Salemi et al. regarding the expression of specific fragments of microRNA (miRNA), particularly miR-132 and miR-212, as potential key regulators in prostate cancer (PCa). As outlined by the Authors, the altered express...
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PAGEPress Publications
2021-10-01
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Series: | Archivio Italiano di Urologia e Andrologia |
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Online Access: | https://pagepressjournals.org/index.php/aiua/article/view/9499 |
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author | Mariano Pontico Viviana Frantellizzi Luca Cindolo Giuseppe De Vincentis |
author_facet | Mariano Pontico Viviana Frantellizzi Luca Cindolo Giuseppe De Vincentis |
author_sort | Mariano Pontico |
collection | DOAJ |
description | To the Editor,
we have been very pleased to read the interesting work proposed by Salemi et al. regarding the expression of specific fragments of microRNA (miRNA), particularly miR-132 and miR-212, as potential key regulators in prostate cancer (PCa). As outlined by the Authors, the altered expression of miRNAs in cancer pathogenesis represents a well-consolidated knowledge in the current literature. More specifically, both miR-212 and miR-132 regulate subsets of genes involved in tumor progression in several tumor cell types as PCa, proving a central role in tumorigenesis, cell adhesion, and angiogenesis. In addition, a strong association between miR-132 expression and high Gleason score PCa has been lately depicted [...]. |
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institution | Directory Open Access Journal |
issn | 1124-3562 2282-4197 |
language | English |
last_indexed | 2024-12-24T03:59:32Z |
publishDate | 2021-10-01 |
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series | Archivio Italiano di Urologia e Andrologia |
spelling | doaj.art-f0d252d7b103486ca0fe3d5a8e449cd92022-12-21T17:16:21ZengPAGEPress PublicationsArchivio Italiano di Urologia e Andrologia1124-35622282-41972021-10-0193310.4081/aiua.2021.3.373Potential prognostic value of miR-132 and miR-212 expression in mCRPC patientsMariano Pontico0Viviana Frantellizzi1Luca Cindolo2Giuseppe De Vincentis3Program in Morphogenesis and Tissue Engineering, Department of Medico-Surgical Sciences and Biotechnologies, Sapienza University of RomeDepartment of Radiological Sciences, Oncology and Anatomical Pathology, Sapienza, “Sapienza” University of RomeDepartment of Urology, "Villa Stuart" Private Hospital, RomeDepartment of Radiological Sciences, Oncology and Anatomical Pathology, Sapienza, “Sapienza” University of RomeTo the Editor, we have been very pleased to read the interesting work proposed by Salemi et al. regarding the expression of specific fragments of microRNA (miRNA), particularly miR-132 and miR-212, as potential key regulators in prostate cancer (PCa). As outlined by the Authors, the altered expression of miRNAs in cancer pathogenesis represents a well-consolidated knowledge in the current literature. More specifically, both miR-212 and miR-132 regulate subsets of genes involved in tumor progression in several tumor cell types as PCa, proving a central role in tumorigenesis, cell adhesion, and angiogenesis. In addition, a strong association between miR-132 expression and high Gleason score PCa has been lately depicted [...].https://pagepressjournals.org/index.php/aiua/article/view/9499Letter to the editor |
spellingShingle | Mariano Pontico Viviana Frantellizzi Luca Cindolo Giuseppe De Vincentis Potential prognostic value of miR-132 and miR-212 expression in mCRPC patients Archivio Italiano di Urologia e Andrologia Letter to the editor |
title | Potential prognostic value of miR-132 and miR-212 expression in mCRPC patients |
title_full | Potential prognostic value of miR-132 and miR-212 expression in mCRPC patients |
title_fullStr | Potential prognostic value of miR-132 and miR-212 expression in mCRPC patients |
title_full_unstemmed | Potential prognostic value of miR-132 and miR-212 expression in mCRPC patients |
title_short | Potential prognostic value of miR-132 and miR-212 expression in mCRPC patients |
title_sort | potential prognostic value of mir 132 and mir 212 expression in mcrpc patients |
topic | Letter to the editor |
url | https://pagepressjournals.org/index.php/aiua/article/view/9499 |
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