Coexistent gastric primary choriocarcinoma and adenocarcinoma
Choriocarcinomas are commonly gestational and intrauterine or gonadal in origin. Nongestational and extragonadal disease, especially in the stomach is extremely rare with a poorer prognosis and early metastasis. We herein describe a case of primary gastric choriocarcinoma with liver metastasis in a...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2009-10-01
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| Series: | Indian Journal of Pathology and Microbiology |
| Subjects: | |
| Online Access: | http://www.ijpmonline.org/article.asp?issn=0377-4929;year=2009;volume=52;issue=4;spage=537;epage=539;aulast=Pai |
| _version_ | 1818962465578287104 |
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| author | Pai Muktha Mathai Alka Kumar Suneet Prabhu Shivananda |
| author_facet | Pai Muktha Mathai Alka Kumar Suneet Prabhu Shivananda |
| author_sort | Pai Muktha |
| collection | DOAJ |
| description | Choriocarcinomas are commonly gestational and intrauterine or gonadal in origin. Nongestational and extragonadal disease, especially in the stomach is extremely rare with a poorer prognosis and early metastasis. We herein describe a case of primary gastric choriocarcinoma with liver metastasis in a 69-year-old male. The patient presented with abdominal pain and irregular bowel habits of one month duration. Both endoscopic and radiographic imaging revealed an ulcerated and necrotic circumferential tumor in the pyloric antrum of the stomach. The histopathologic findings of the resected tumor were that of an extensively necrotic and hemorrhagic neoplasm with combined choriocarcinomatous and adenocarcinomatous element. A strongly positive immunohistochemical staining for β- subunit of human chorionic gonadotropin (β-HCG) in the choriocarcinomatous component and a proper correlation with elevated serum β-HCG levels confirmed the diagnosis. |
| first_indexed | 2024-12-20T12:29:45Z |
| format | Article |
| id | doaj.art-f0d417cb4284452688e9745cf3a54bb8 |
| institution | Directory Open Access Journal |
| issn | 0377-4929 0974-5130 |
| language | English |
| last_indexed | 2024-12-20T12:29:45Z |
| publishDate | 2009-10-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Indian Journal of Pathology and Microbiology |
| spelling | doaj.art-f0d417cb4284452688e9745cf3a54bb82022-12-21T19:40:46ZengWolters Kluwer Medknow PublicationsIndian Journal of Pathology and Microbiology0377-49290974-51302009-10-01524537539Coexistent gastric primary choriocarcinoma and adenocarcinomaPai MukthaMathai AlkaKumar SuneetPrabhu ShivanandaChoriocarcinomas are commonly gestational and intrauterine or gonadal in origin. Nongestational and extragonadal disease, especially in the stomach is extremely rare with a poorer prognosis and early metastasis. We herein describe a case of primary gastric choriocarcinoma with liver metastasis in a 69-year-old male. The patient presented with abdominal pain and irregular bowel habits of one month duration. Both endoscopic and radiographic imaging revealed an ulcerated and necrotic circumferential tumor in the pyloric antrum of the stomach. The histopathologic findings of the resected tumor were that of an extensively necrotic and hemorrhagic neoplasm with combined choriocarcinomatous and adenocarcinomatous element. A strongly positive immunohistochemical staining for β- subunit of human chorionic gonadotropin (β-HCG) in the choriocarcinomatous component and a proper correlation with elevated serum β-HCG levels confirmed the diagnosis.http://www.ijpmonline.org/article.asp?issn=0377-4929;year=2009;volume=52;issue=4;spage=537;epage=539;aulast=PaiAdenocarcinomachoriocarcinomagastric tumorβ-human chorionic gonadotropinliver metastasis |
| spellingShingle | Pai Muktha Mathai Alka Kumar Suneet Prabhu Shivananda Coexistent gastric primary choriocarcinoma and adenocarcinoma Indian Journal of Pathology and Microbiology Adenocarcinoma choriocarcinoma gastric tumor β-human chorionic gonadotropin liver metastasis |
| title | Coexistent gastric primary choriocarcinoma and adenocarcinoma |
| title_full | Coexistent gastric primary choriocarcinoma and adenocarcinoma |
| title_fullStr | Coexistent gastric primary choriocarcinoma and adenocarcinoma |
| title_full_unstemmed | Coexistent gastric primary choriocarcinoma and adenocarcinoma |
| title_short | Coexistent gastric primary choriocarcinoma and adenocarcinoma |
| title_sort | coexistent gastric primary choriocarcinoma and adenocarcinoma |
| topic | Adenocarcinoma choriocarcinoma gastric tumor β-human chorionic gonadotropin liver metastasis |
| url | http://www.ijpmonline.org/article.asp?issn=0377-4929;year=2009;volume=52;issue=4;spage=537;epage=539;aulast=Pai |
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