IGFBP7 and GDF-15, but not P1NP, are associated with cardiac alterations and 10-year outcome in an elderly community-based study

IGFBP7 and GDF-15, but not P1NP, are associated with cardiac alterations and 10-year outcome in an elderly community-based study

Abstract Background Little is known about the clinical value of Insulin-like growth factor-binding protein-7 (IGFBP7), a cellular senescence marker, in an elderly general population with multiple co-morbidities and high prevalence of asymptomatic cardiovascular ventricular dysfunction. Inflammation...

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Bibliographic Details
Main Authors: Jennifer M. T. A. Meessen, Giulia Cesaroni, Gian F. Mureddu, Alessandro Boccanelli, Ursula-Henrike Wienhues-Thelen, Peter Kastner, Luisa Ojeda-Fernandez, Deborah Novelli, Gianfranco Bazzoni, Maurizio Mangiavacchi, Nera Agabiti, Serge Masson, Lidia Staszewsky, Roberto Latini, on behalf of the PREDICTOR Investigators
Format: Article
Language:English
Published: BMC 2021-07-01
Series:BMC Cardiovascular Disorders
Subjects:
IGFBP7
GDF-15
P1NP
Cardiac remodelling
Community-dwelling elderly
Online Access:https://doi.org/10.1186/s12872-021-02138-8

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