Development of Floating Tablets of Metformin HCl by Thermoplastic Granulation. Part II: In Vitro Evaluation of the Combined Effect of Acacia Gum/HPMC on Biopharmaceutical Performances

Development of Floating Tablets of Metformin HCl by Thermoplastic Granulation. Part II: In Vitro Evaluation of the Combined Effect of Acacia Gum/HPMC on Biopharmaceutical Performances

Purpose: The aim of this study was to evaluate the combined effect, acacia gum(AG)/ hydroxypropylmethylcellulose (HPMC), on biopharmaceutical performances of floating tablets of metformin hydrochloride (MTH) prepared by thermoplastic granulation using stearic acid. Methods: We have prepared the matr...

Full description

Bibliographic Details
Main Authors:	Mohamed Djebbar, Nacéra Chaffai, Fatiha Bouchal
Format:	Article
Language:	English
Published:	Tabriz University of Medical Sciences 2020-05-01
Series:	Advanced Pharmaceutical Bulletin
Subjects:	acacia gum acacia gum/hpmc combination floating tablets metformin hcl stearic acid thermoplastic granulation
Online Access:	https://apb.tbzmed.ac.ir/PDF/apb-27688

Similar Items

Gum Arabia : the backbone of Kordofan region, Sudan /
by: 329773 Muthana, K. D., et al.

Exploring the Role of Acacia (<i>Acacia seyal</i>) and Cactus (<i>Opuntia ficus-indica</i>) Gums on the Dough Performance and Quality Attributes of Breads and Cakes
by: Shahzad Hussain, et al.
Published: (2022-04-01)

Blend of guar/acacia gum as a partial substitute of lecithin in white chocolate: Optimization, characterization, and shelf-life evaluation
by: Harshvardhan Patel, et al.
Published: (2024-03-01)

Improving the biological properties of berberine by using gellan and gum acacia as a potential delivery carrier
by: Jyoti Bakshi, et al.
Published: (2023-12-01)

Characteristics and quality of gum arabic derived from naturally grown Acacia seyal Willdenow tree in the lowland areas of Ethiopia
by: Gemechu Jebeso, et al.
Published: (2023-10-01)

A Review on the Main Phytoconstituents, Traditional Uses, Inventions, and Patent Literature of Gum Arabic Emphasizing <i>Acacia seyal</i>
by: Mohamed A. Ashour, et al.
Published: (2022-02-01)

Preparation and In-Vitro Evaluation of Sustained Release Matrix Diclofenac Sodium Tablets Using HPMC KM 100 and Gums
by: Zafar Iqbal, Raza Khan, Fazli Nasir, Jamshaid Ali Khan, Lateef Ahmad, Abad Khan, Yaser Shah, et al.
Published: (2010-12-01)

Evaluation of the analgesic and anesthetic properties of silver nanoparticles supported over biodegradable acacia gum-modified magnetic nanoparticles
by: Tan Binbin, et al.
Published: (2023-12-01)

Wound Dressing: Combination of Acacia Gum/PVP/Cyclic Dextrin in Bioadhesive Patches Loaded with Grape Seed Extract
by: Cinzia Pagano, et al.
Published: (2022-02-01)

Gum Acacia Functionalized Colloidal Gold Nanoparticles of Letrozole as Biocompatible Drug Delivery Carrier for Treatment of Breast Cancer
by: Hibah M. Aldawsari, et al.
Published: (2021-09-01)

The Effect of Gum Arabic (<i>Acacia senegal</i>) on Cardiovascular Risk Factors and Gastrointestinal Symptoms in Adults at Risk of Metabolic Syndrome: A Randomized Clinical Trial
by: Amjad H. Jarrar, et al.
Published: (2021-01-01)

Effect of Cactus (<i>Opuntia ficus-indica</i>) and Acacia (<i>Acacia seyal</i>) Gums on the Pasting, Thermal, Textural, and Rheological Properties of Corn, Sweet Potato, and Turkish Bean Starches
by: Shahzad Hussain, et al.
Published: (2022-01-01)

Safety and efficacy of a feed additive consisting of acacia gum (gum Arabic) for all animal species (A.I.P.G. Association for International Promotion of Gums)
by: EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP), et al.
Published: (2022-04-01)

Influence of Drought on <i>Acacia senegal</i> (L.) Willd: Gum Yield within a Soil Moisture Gradient in North Eastern Nigeria
by: A.U. Jibo
Published: (2021-11-01)

Identification of acacia gum fermenting bacteria from pooled human feces using anaerobic enrichment culture
by: Muhamad Hanif Rawi, et al.
Published: (2023-10-01)

Acacia Gum Is Well Tolerated While Increasing Satiety and Lowering Peak Blood Glucose Response in Healthy Human Subjects
by: Riley Larson, et al.
Published: (2021-02-01)

Mechanical Properties of Partial Replacement of Cement by adding Neem Gum/Accaacia Gum a Naturally Available Polymeric Fillers
by: S Ida blessy, et al.
Published: (2023-07-01)

Improved Mucoadhesion, Permeation and In Vitro Anticancer Potential of Synthesized Thiolated Acacia and Karaya Gum Combination: A Systematic Study
by: Neha Munot, et al.
Published: (2022-10-01)

Extraction of bioactive compound from Acacia seyal gum, in vitro evaluation of antitumor activity of its crude extract against leukemia
by: Nassereldeen Kabbashi, et al.
Published: (2022-01-01)

Physicochemical properties of soy protein isolates-acacia gum conjugates
by: Lixia Mu, et al.
Published: (2011-04-01)

Increased <i>Hirsutella citriformis</i> Conidia Shelf Life in <i>Acacia</i> and <i>Hirsutella</i> Gum Formulations
by: Rosa A. Flores-Villarreal, et al.
Published: (2023-07-01)

Enhancing semen quality, brain neurotransmitters, and antioxidant status of rabbits under heat stress by acacia gum, vitamin C, and lycopene as dietary supplements: an in vitro and in silico study
by: Tharwat A. Imbabi, et al.
Published: (2023-12-01)

Development of Gum-Acacia-Stabilized Silver Nanoparticles Gel of Rutin against <i>Candida albicans</i>
by: Mohammed H. Alqarni, et al.
Published: (2022-07-01)

Aplikasi enkapsulan hydroxy propyl methyl cellulose dan gum arab pada pembuatan bubuk semangka
by: Ignasius Radix AP Jati, et al.
Published: (2023-12-01)

Site adaptability of acacia mangium, acacia auriculiformis, acacia crassicarpa and acacia aulacocarpa /
by: 219632 Ahmed Eldoma, et al.
Published: (1999)

The Efficacy of Gum Arabic in Managing Diseases: A Systematic Review of Evidence-Based Clinical Trials
by: Yamamh Al-Jubori, et al.
Published: (2023-01-01)

Microencapsulation of Peppermint Oil by Complex Coacervation and Subsequent Spray Drying Using Bovine Serum Albumin/Gum Acacia and an Oxidized Starch Crosslinker
by: Wilhelm Robert Glomm, et al.
Published: (2021-04-01)

Toxicity Assessment and Control of Early Blight and Stem Rot of <i>Solanum tuberosum</i> L. by Mancozeb-Loaded Chitosan–Gum Acacia Nanocomposites
by: Ravinder Kumar, et al.
Published: (2022-04-01)

ESTABLISHING OF THE CONDITIONS OF THE BLEND OF PULP WITH BANANA (<I>Musa paradisiaca</I> L.) TO SUBMIT SPRAY DRYNG
by: Beatriz E. LOPEZ M., et al.
Published: (2009-11-01)

Gum Acacia Stabilized Ag-TiO<sub>2</sub> and Ag-SiO<sub>2</sub>: Sustainable Nanocatalysts for Direct and Convenient Synthesis of 5-Substituted 1<i>H</i>-tetrazoles
by: Supriya Prakash, et al.
Published: (2023-11-01)

Optimization of Ultrasound-Assisted Extraction of Bioactive Compounds from <i>Acacia Seyal</i> Gum Using Response Surface Methodology and Their Chemical Content Identification by Raman, FTIR, and GC-TOFMS
by: Tahani Maher, et al.
Published: (2021-10-01)

Fabrication of Spray-Dried Microcapsules Containing Noni Juice Using Blends of Maltodextrin and Gum Acacia: Physicochemical Properties of Powders and Bioaccessibility of Bioactives during In Vitro Digestion
by: Chuang Zhang, et al.
Published: (2020-09-01)

Surface modified Acacia Senegal Gum based spherical hydrogel; fabrication, characterization, and kinetically optimized waste water treatment with remarkable adsorption efficiency
by: Rasha M.K. Mohamed
Published: (2023-06-01)

Performance of Acacia Gum as a Novel Additive in Thin Film Composite Polyamide RO Membranes
by: Yehia Manawi, et al.
Published: (2019-02-01)

Improved <i>Diaphorina citri</i> (Hemiptera: Liviidae) Adults Biocontrol in Citrus by <i>Hirsutella citriformis</i> (Hypocreales: Ophiocordycipitaceae) Gum-Enhanced Conidia Formulation
by: Orquídea Pérez-González, et al.
Published: (2023-03-01)

Proceedings of the Seminar on the Potential of Acacia and other Plantation Species /
by: Lembaga Perindustrian Kayu Malaysia, et al.
Published: ([199)

Breeding Strategy of Acacia Hybrid (Acacia mangium × A. auriculiformis) to Increase Forest Plantation Productivity in Indonesia
by: Sri Sunarti, et al.
Published: (2013-08-01)

Fabrication, Characterization, and Antioxidant Potential of Sodium Alginate/Acacia Gum Hydrogel-Based Films Loaded with Cinnamon Essential Oil
by: Saurabh Bhatia, et al.
Published: (2023-04-01)

Effect of acacia exudate gum on milk gel fermentation of flavoured synbiotic yoghurt enriched with Daucus carota L. ssp. sativus var. atrorubens Alef fibre
by: Tulay Ozcan, et al.
Published: (2021-01-01)

Acacias in perfumery...mimosa and cassie ancienne /
by: 355333 Peyron, L.