The Receptor-Binding Domain in the VP1u Region of Parvovirus B19

The Receptor-Binding Domain in the VP1u Region of Parvovirus B19

Parvovirus B19 (B19V) is known as the human pathogen causing the mild childhood disease erythema infectiosum. B19V shows an extraordinary narrow tissue tropism for erythroid progenitor cells in the bone marrow, which is determined by a highly restricted uptake. We have previously shown that the spec...

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Bibliographic Details
Main Authors: Remo Leisi, Chiarina Di Tommaso, Christoph Kempf, Carlos Ros
Format: Article
Language:English
Published: MDPI AG 2016-02-01
Series:Viruses
Subjects:
parvovirus B19
virus entry
VP1u
receptor-binding domain
immunodominant region
Online Access:http://www.mdpi.com/1999-4915/8/3/61

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