Anemia in early congenital syphilis

The determination of blood parameters allowed us to establish that anemia develops in a number of infectious diseases, which is called "anemia of inflammation" or anemia of chronic diseases. The article presents a rare clinical case of the development of anemia of the inflammatory response...

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Main Authors: А. V. Vislobokov, R. A. Khmel'nitskij
Format: Article
Language:English
Published: State Scientific Center of Dermatovenereology and Cosmetology 2021-12-01
Series:Vestnik Dermatologii i Venerologii
Subjects:
Online Access:https://vestnikdv.ru/jour/article/viewFile/1250/pdf
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author А. V. Vislobokov
R. A. Khmel'nitskij
author_facet А. V. Vislobokov
R. A. Khmel'nitskij
author_sort А. V. Vislobokov
collection DOAJ
description The determination of blood parameters allowed us to establish that anemia develops in a number of infectious diseases, which is called "anemia of inflammation" or anemia of chronic diseases. The article presents a rare clinical case of the development of anemia of the inflammatory response, accompanied by a marked decrease in the content of hemoglobin (less than 110 g/l), hematocrit (less than 30%) and red blood cells (less than 3,0 х 1012/l), in a child with early congenital syphilis with symptoms of: specific rhinitis, papular infiltration, pemphigus, hepatosplenomegaly and damage to the nervous system. As a result of specific treatment with water-soluble benzylpenicillin salt at the rate of 100 U/kg of body weight for 28 days, and transfusion of erythrocyte mass of 15 ml/kg of child weight, there was a parallel regression of clinical manifestations of syphilis with positive dynamics of serological reactions and restoration of the number of red blood cells and the concentration of hemoglobin in the blood.
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spelling doaj.art-f0db667d4ef64946b6230b7d1cc097242023-09-02T13:44:38ZengState Scientific Center of Dermatovenereology and CosmetologyVestnik Dermatologii i Venerologii0042-46092313-62942021-12-01975889310.25208/vdv12501123Anemia in early congenital syphilisА. V. Vislobokov0https://orcid.org/0000-0003-2484-1827R. A. Khmel'nitskij1https://orcid.org/0000-0002-1128-9239Oryol Skin-Venereologic DispensaryOryol Skin-Venereologic DispensaryThe determination of blood parameters allowed us to establish that anemia develops in a number of infectious diseases, which is called "anemia of inflammation" or anemia of chronic diseases. The article presents a rare clinical case of the development of anemia of the inflammatory response, accompanied by a marked decrease in the content of hemoglobin (less than 110 g/l), hematocrit (less than 30%) and red blood cells (less than 3,0 х 1012/l), in a child with early congenital syphilis with symptoms of: specific rhinitis, papular infiltration, pemphigus, hepatosplenomegaly and damage to the nervous system. As a result of specific treatment with water-soluble benzylpenicillin salt at the rate of 100 U/kg of body weight for 28 days, and transfusion of erythrocyte mass of 15 ml/kg of child weight, there was a parallel regression of clinical manifestations of syphilis with positive dynamics of serological reactions and restoration of the number of red blood cells and the concentration of hemoglobin in the blood.https://vestnikdv.ru/jour/article/viewFile/1250/pdfсongenital syphilisanemiadiagnosticstreatment
spellingShingle А. V. Vislobokov
R. A. Khmel'nitskij
Anemia in early congenital syphilis
Vestnik Dermatologii i Venerologii
сongenital syphilis
anemia
diagnostics
treatment
title Anemia in early congenital syphilis
title_full Anemia in early congenital syphilis
title_fullStr Anemia in early congenital syphilis
title_full_unstemmed Anemia in early congenital syphilis
title_short Anemia in early congenital syphilis
title_sort anemia in early congenital syphilis
topic сongenital syphilis
anemia
diagnostics
treatment
url https://vestnikdv.ru/jour/article/viewFile/1250/pdf
work_keys_str_mv AT avvislobokov anemiainearlycongenitalsyphilis
AT rakhmelnitskij anemiainearlycongenitalsyphilis