From Gene-for-Gene to Resistosomes: Flor's Enduring Legacy
The gene-for-gene model proposed by H. H. Flor has been one of the fundamental precepts of plant-pathogen interactions that has underpinned decades of research towards our current concepts of plant immunity. The broad validity of this model as an elegant and accurate genetic description of specific...
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| Format: | Article |
| Language: | English |
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The American Phytopathological Society
2023-08-01
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| Series: | Molecular Plant-Microbe Interactions |
| Subjects: | |
| Online Access: | https://apsjournals.apsnet.org/doi/10.1094/MPMI-06-23-0081-HH |
| _version_ | 1797687088590618624 |
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| author | Peter N. Dodds |
| author_facet | Peter N. Dodds |
| author_sort | Peter N. Dodds |
| collection | DOAJ |
| description | The gene-for-gene model proposed by H. H. Flor has been one of the fundamental precepts of plant-pathogen interactions that has underpinned decades of research towards our current concepts of plant immunity. The broad validity of this model as an elegant and accurate genetic description of specific recognition events between the products of plant resistance (R) and pathogen avirulence (Avr) genes has been demonstrated many times over in a wide variety of plant disease systems. In recent years detailed molecular and structural analyses have provided a deep understanding of the principles by which plant immune receptors recognize pathogen effectors, including providing molecular descriptions of many of the genetic loci in flax and flax rust characterized by Flor. Recent advances in molecular and structural understanding of immune receptor recognition and activation mechanisms have brought the field to a new level, where rational design of novel receptors through engineering approaches is becoming a realizable goal. [Graphic: see text] Copyright © 2023 The Author(s). This is an open access article distributed under the CC BY-NC-ND 4.0 International license. |
| first_indexed | 2024-03-12T01:14:13Z |
| format | Article |
| id | doaj.art-f0e0e1e3e292433c82dc07a68370a28d |
| institution | Directory Open Access Journal |
| issn | 0894-0282 1943-7706 |
| language | English |
| last_indexed | 2024-03-12T01:14:13Z |
| publishDate | 2023-08-01 |
| publisher | The American Phytopathological Society |
| record_format | Article |
| series | Molecular Plant-Microbe Interactions |
| spelling | doaj.art-f0e0e1e3e292433c82dc07a68370a28d2023-09-14T00:39:54ZengThe American Phytopathological SocietyMolecular Plant-Microbe Interactions0894-02821943-77062023-08-0136846146710.1094/MPMI-06-23-0081-HHFrom Gene-for-Gene to Resistosomes: Flor's Enduring LegacyPeter N. Dodds0CSIRO Agriculture and Food, GPO Box 1700, Clunies Ross Street, Canberra 2601, AustraliaThe gene-for-gene model proposed by H. H. Flor has been one of the fundamental precepts of plant-pathogen interactions that has underpinned decades of research towards our current concepts of plant immunity. The broad validity of this model as an elegant and accurate genetic description of specific recognition events between the products of plant resistance (R) and pathogen avirulence (Avr) genes has been demonstrated many times over in a wide variety of plant disease systems. In recent years detailed molecular and structural analyses have provided a deep understanding of the principles by which plant immune receptors recognize pathogen effectors, including providing molecular descriptions of many of the genetic loci in flax and flax rust characterized by Flor. Recent advances in molecular and structural understanding of immune receptor recognition and activation mechanisms have brought the field to a new level, where rational design of novel receptors through engineering approaches is becoming a realizable goal. [Graphic: see text] Copyright © 2023 The Author(s). This is an open access article distributed under the CC BY-NC-ND 4.0 International license.https://apsjournals.apsnet.org/doi/10.1094/MPMI-06-23-0081-HHavirulencedisease resistanceimmune receptor recognitionnovel receptors |
| spellingShingle | Peter N. Dodds From Gene-for-Gene to Resistosomes: Flor's Enduring Legacy Molecular Plant-Microbe Interactions avirulence disease resistance immune receptor recognition novel receptors |
| title | From Gene-for-Gene to Resistosomes: Flor's Enduring Legacy |
| title_full | From Gene-for-Gene to Resistosomes: Flor's Enduring Legacy |
| title_fullStr | From Gene-for-Gene to Resistosomes: Flor's Enduring Legacy |
| title_full_unstemmed | From Gene-for-Gene to Resistosomes: Flor's Enduring Legacy |
| title_short | From Gene-for-Gene to Resistosomes: Flor's Enduring Legacy |
| title_sort | from gene for gene to resistosomes flor s enduring legacy |
| topic | avirulence disease resistance immune receptor recognition novel receptors |
| url | https://apsjournals.apsnet.org/doi/10.1094/MPMI-06-23-0081-HH |
| work_keys_str_mv | AT peterndodds fromgeneforgenetoresistosomesflorsenduringlegacy |