Side-chain Modifications of Highly Functionalized 3(2H)-Furanones
A series of 3(2H)-furanones, based on side-chain modifications of a parent 3(2H)-furanone, was synthesized in good yield. The parent compound was prepared by hydrogenolysis, and subsequent acid hydrolysis, of isoxazole derivatives. The isoxazole was prepared by a [3+2] 1,3-dipolar cycloaddition reac...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2012-10-01
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| Series: | Molecules |
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| Online Access: | http://www.mdpi.com/1420-3049/17/10/12151 |
| _version_ | 1818289845675491328 |
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| author | Gil Valdo José da Silva Maurício Gomes Constantino Viviani Nardini Shirley Muniz Machado Rodrigues |
| author_facet | Gil Valdo José da Silva Maurício Gomes Constantino Viviani Nardini Shirley Muniz Machado Rodrigues |
| author_sort | Gil Valdo José da Silva |
| collection | DOAJ |
| description | A series of 3(2H)-furanones, based on side-chain modifications of a parent 3(2H)-furanone, was synthesized in good yield. The parent compound was prepared by hydrogenolysis, and subsequent acid hydrolysis, of isoxazole derivatives. The isoxazole was prepared by a [3+2] 1,3-dipolar cycloaddition reaction between 3-butyn-2-ol and nitrile oxide. |
| first_indexed | 2024-12-13T02:18:45Z |
| format | Article |
| id | doaj.art-f0e3028a8d9240f6ba9ea3288517267f |
| institution | Directory Open Access Journal |
| issn | 1420-3049 |
| language | English |
| last_indexed | 2024-12-13T02:18:45Z |
| publishDate | 2012-10-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Molecules |
| spelling | doaj.art-f0e3028a8d9240f6ba9ea3288517267f2022-12-22T00:02:50ZengMDPI AGMolecules1420-30492012-10-011710121511216210.3390/molecules171012151Side-chain Modifications of Highly Functionalized 3(2H)-FuranonesGil Valdo José da SilvaMaurício Gomes ConstantinoViviani NardiniShirley Muniz Machado RodriguesA series of 3(2H)-furanones, based on side-chain modifications of a parent 3(2H)-furanone, was synthesized in good yield. The parent compound was prepared by hydrogenolysis, and subsequent acid hydrolysis, of isoxazole derivatives. The isoxazole was prepared by a [3+2] 1,3-dipolar cycloaddition reaction between 3-butyn-2-ol and nitrile oxide.http://www.mdpi.com/1420-3049/17/10/121513(2H)-furanoneisoxazolenatural productsside-chain modifications |
| spellingShingle | Gil Valdo José da Silva Maurício Gomes Constantino Viviani Nardini Shirley Muniz Machado Rodrigues Side-chain Modifications of Highly Functionalized 3(2H)-Furanones Molecules 3(2H)-furanone isoxazole natural products side-chain modifications |
| title | Side-chain Modifications of Highly Functionalized 3(2H)-Furanones |
| title_full | Side-chain Modifications of Highly Functionalized 3(2H)-Furanones |
| title_fullStr | Side-chain Modifications of Highly Functionalized 3(2H)-Furanones |
| title_full_unstemmed | Side-chain Modifications of Highly Functionalized 3(2H)-Furanones |
| title_short | Side-chain Modifications of Highly Functionalized 3(2H)-Furanones |
| title_sort | side chain modifications of highly functionalized 3 2h furanones |
| topic | 3(2H)-furanone isoxazole natural products side-chain modifications |
| url | http://www.mdpi.com/1420-3049/17/10/12151 |
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