MAIT Cells Balance the Requirements for Immune Tolerance and Anti-Microbial Defense During Pregnancy

MAIT Cells Balance the Requirements for Immune Tolerance and Anti-Microbial Defense During Pregnancy

Mucosal-associated invariant T (MAIT) cells are an innate-like T cell subset with proinflammatory and cytotoxic effector functions. During pregnancy, modulation of the maternal immune system, both at the fetal-maternal interface and systemically, is crucial for a successful outcome and manifests thr...

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Bibliographic Details
Main Authors: Johanna Raffetseder, Robert Lindau, Sigrid van der Veen, Göran Berg, Marie Larsson, Jan Ernerudh
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Immunology
Subjects:
mucosal-associated invariant T (MAIT) cells
pregnancy
innate-like T cells
decidua
T cells
immune tolerance
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.718168/full

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