Unexpected chiral vicinal tetrasubstituted diamines via borylcopper-mediated homocoupling of isatin imines

Unexpected chiral vicinal tetrasubstituted diamines via borylcopper-mediated homocoupling of isatin imines

Addressing the asymmetric synthesis of oxindole-based α-aminoboronic acids, instead of the expected products we disclosed the efficient homocoupling of oxindole-based N-tert-butanesulfinyl imines, with the generation of chiral, quaternary 1,2-diamines in a mild and completely stereoselective way. Th...

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Bibliographic Details
Main Authors:	Marco Manenti, Leonardo Lo Presti, Giorgio Molteni, Alessandra Silvani
Format:	Article
Language:	English
Published:	Beilstein-Institut 2022-03-01
Series:	Beilstein Journal of Organic Chemistry
Subjects:	atropoisomer bis(pinacolato)diboron 3,3′-bisoxindole n-tert-butanesulfinyl ketimine homocoupling
Online Access:	https://doi.org/10.3762/bjoc.18.34

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