Fast test for assessing the susceptibility of Mycobacterium tuberculosis to isoniazid and rifampin by real-time PCR

Fast test for assessing the susceptibility of Mycobacterium tuberculosis to isoniazid and rifampin by real-time PCR

Mycobacterium tuberculosis is the bacterium that causes tuberculosis (TB), a leading cause of death from infectious disease worldwide. Rapid diagnosis of resistant strains is important for the control of TB. Real-time polymerase chain reaction (RT-PCR) assays may detect all of the mutations that occ...

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Bibliographic Details
Main Authors: Maria Gisele Gonçalves, Lucila Okuyama Fukasawa, Rosangela Siqueira Oliveira, Maristela Marques Salgado, Lee H Harrison, Kathleen A Shutt, Claudio Tavares Sacchi
Format: Article
Language:English
Published: Fundação Oswaldo Cruz (FIOCRUZ) 2012-11-01
Series:Memorias do Instituto Oswaldo Cruz
Subjects:
Mycobacterium tuberculosis
RT-PCR
drug resistance
INH
RIF
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762012000700011&lng=en&tlng=en

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