IgA nephropathy presenting with pulmonary thromboembolism and renal artery infarct
Background: Venous and arterial thromboembolism are frequently seen in nephrotic syndrome. They generally occur during periods of sustained proteinuria in patients who are not responding to treatment and more commonly seen in minimal change disease and membranous nephropathy. Case Presentation: A 28...
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| Format: | Article |
| Language: | English |
| Published: |
Society of Diabetic Nephropathy Prevention
2019-07-01
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| Series: | Journal of Nephropathology |
| Subjects: | |
| Online Access: | https://nephropathol.com/PDF/jnp-8-e29.pdf |
| _version_ | 1797828014827896832 |
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| author | Madhav Venkatesan Anil Mathew Rajesh Nair George Kurian Seethalekshmy NV Sandeep Sreedharan Zachariah Paul |
| author_facet | Madhav Venkatesan Anil Mathew Rajesh Nair George Kurian Seethalekshmy NV Sandeep Sreedharan Zachariah Paul |
| author_sort | Madhav Venkatesan |
| collection | DOAJ |
| description | Background: Venous and arterial thromboembolism are frequently seen in nephrotic syndrome. They generally occur during periods of sustained proteinuria in patients who are not responding to treatment and more commonly seen in minimal change disease and membranous nephropathy. Case Presentation: A 28-year-old male presented to cardiology department of our hospital with worsening breathlessness for 1 week. We found pulmonary embolism and an infarct in the lower pole of the right kidney by CT pulmonary angiogram. He had no previous history or features of nephrotic syndrome. Urine analysis showed numerous red blood cells, 3+ proteinuria and granular casts. Urine protein creatinine ratio was 5.2 g/g of creatinine. Serum creatinine was 2.61 mg/dL. Renal biopsy was suggestive of IgA nephropathy and patient was started on steroids and warfarin and responded to treatment. Conclusions: Patients with nephrotic syndrome can rarely present initially with venous and arterial thromboembolism. Rarely even IgA nephropathy can present with such thromboembolic episodes. |
| first_indexed | 2024-04-09T12:57:41Z |
| format | Article |
| id | doaj.art-f0eae55e8cd54561bf4972ed6fc7ea98 |
| institution | Directory Open Access Journal |
| issn | 2251-8363 2251-8819 |
| language | English |
| last_indexed | 2024-04-09T12:57:41Z |
| publishDate | 2019-07-01 |
| publisher | Society of Diabetic Nephropathy Prevention |
| record_format | Article |
| series | Journal of Nephropathology |
| spelling | doaj.art-f0eae55e8cd54561bf4972ed6fc7ea982023-05-13T11:27:59ZengSociety of Diabetic Nephropathy PreventionJournal of Nephropathology2251-83632251-88192019-07-0183e29e2910.15171/jnp.2019.29jnp-1543IgA nephropathy presenting with pulmonary thromboembolism and renal artery infarctMadhav Venkatesan0Anil Mathew1Rajesh Nair2George Kurian3Seethalekshmy NV4Sandeep Sreedharan5Zachariah Paul6Department of Nephrology, Amrita Institute of Medical Sciences, Kochi, IndiaDepartment of Nephrology, Amrita Institute of Medical Sciences, Kochi, IndiaDepartment of Nephrology, Amrita Institute of Medical Sciences, Kochi, IndiaDepartment of Nephrology, Amrita Institute of Medical Sciences, Kochi, IndiaDepartment of Pathology, Amrita Institute of Medical Sciences, Kochi, IndiaDepartment of Nephrology, Amrita Institute of Medical Sciences, Kochi, IndiaDepartment of Nephrology, Amrita Institute of Medical Sciences, Kochi, IndiaBackground: Venous and arterial thromboembolism are frequently seen in nephrotic syndrome. They generally occur during periods of sustained proteinuria in patients who are not responding to treatment and more commonly seen in minimal change disease and membranous nephropathy. Case Presentation: A 28-year-old male presented to cardiology department of our hospital with worsening breathlessness for 1 week. We found pulmonary embolism and an infarct in the lower pole of the right kidney by CT pulmonary angiogram. He had no previous history or features of nephrotic syndrome. Urine analysis showed numerous red blood cells, 3+ proteinuria and granular casts. Urine protein creatinine ratio was 5.2 g/g of creatinine. Serum creatinine was 2.61 mg/dL. Renal biopsy was suggestive of IgA nephropathy and patient was started on steroids and warfarin and responded to treatment. Conclusions: Patients with nephrotic syndrome can rarely present initially with venous and arterial thromboembolism. Rarely even IgA nephropathy can present with such thromboembolic episodes.https://nephropathol.com/PDF/jnp-8-e29.pdfiga nephropathynephrotic syndromearterial thromboembolismproteinuria |
| spellingShingle | Madhav Venkatesan Anil Mathew Rajesh Nair George Kurian Seethalekshmy NV Sandeep Sreedharan Zachariah Paul IgA nephropathy presenting with pulmonary thromboembolism and renal artery infarct Journal of Nephropathology iga nephropathy nephrotic syndrome arterial thromboembolism proteinuria |
| title | IgA nephropathy presenting with pulmonary thromboembolism and renal artery infarct |
| title_full | IgA nephropathy presenting with pulmonary thromboembolism and renal artery infarct |
| title_fullStr | IgA nephropathy presenting with pulmonary thromboembolism and renal artery infarct |
| title_full_unstemmed | IgA nephropathy presenting with pulmonary thromboembolism and renal artery infarct |
| title_short | IgA nephropathy presenting with pulmonary thromboembolism and renal artery infarct |
| title_sort | iga nephropathy presenting with pulmonary thromboembolism and renal artery infarct |
| topic | iga nephropathy nephrotic syndrome arterial thromboembolism proteinuria |
| url | https://nephropathol.com/PDF/jnp-8-e29.pdf |
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