The Management of Scabies in the 21st Century: Past, Advances and Potentials

Scabies is one of the most common skin diseases worldwide, affecting 150–200 million people yearly. Scabies affects young children in particular, and has the greatest impact in poor overcrowded living conditions. The burden of the disease is now well characterized, including group A Streptococcus an...

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Main Authors: Charlotte Bernigaud, Katja Fischer, Olivier Chosidow
Format: Article
Language:English
Published: Medical Journals Sweden 2020-04-01
Series:Acta Dermato-Venereologica
Subjects:
Online Access: https://www.medicaljournals.se/acta/content/html/10.2340/00015555-3468
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author Charlotte Bernigaud
Katja Fischer
Olivier Chosidow
author_facet Charlotte Bernigaud
Katja Fischer
Olivier Chosidow
author_sort Charlotte Bernigaud
collection DOAJ
description Scabies is one of the most common skin diseases worldwide, affecting 150–200 million people yearly. Scabies affects young children in particular, and has the greatest impact in poor overcrowded living conditions. The burden of the disease is now well characterized, including group A Streptococcus and Staphylococcus aureus bacterial superinfections, with reports of nephritis, acute rheumatic fever, or fatal invasive sepsis secondary to scabies. Management of scabies remains largely suboptimal from diagnosis to treatment, and progress in the development of new therapeutic measures leading to cure is urgently needed. This review gives an overview of the current limitations in the management of scabies, an update on recent advances, and outlines prospects for potential improvements.
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spelling doaj.art-f0eb6dfca95f45f1a69e3c954515f9d22022-12-22T01:39:31ZengMedical Journals SwedenActa Dermato-Venereologica0001-55551651-20572020-04-011009adv0011210.2340/00015555-34685727The Management of Scabies in the 21st Century: Past, Advances and PotentialsCharlotte Bernigaud0Katja FischerOlivier Chosidow Department of Dermatology, AP-HP, Hôpital Henri Mondor, FR-94010 Créteil, France. charlotte.bernigaud@aphp.fr. Scabies is one of the most common skin diseases worldwide, affecting 150–200 million people yearly. Scabies affects young children in particular, and has the greatest impact in poor overcrowded living conditions. The burden of the disease is now well characterized, including group A Streptococcus and Staphylococcus aureus bacterial superinfections, with reports of nephritis, acute rheumatic fever, or fatal invasive sepsis secondary to scabies. Management of scabies remains largely suboptimal from diagnosis to treatment, and progress in the development of new therapeutic measures leading to cure is urgently needed. This review gives an overview of the current limitations in the management of scabies, an update on recent advances, and outlines prospects for potential improvements. https://www.medicaljournals.se/acta/content/html/10.2340/00015555-3468 scabies sarcoptes scabiei neglected tropical disease ivermectin permethrin moxidectin acaricide discovery and development ovicidal
spellingShingle Charlotte Bernigaud
Katja Fischer
Olivier Chosidow
The Management of Scabies in the 21st Century: Past, Advances and Potentials
Acta Dermato-Venereologica
scabies
sarcoptes scabiei
neglected tropical disease
ivermectin
permethrin
moxidectin
acaricide discovery and development
ovicidal
title The Management of Scabies in the 21st Century: Past, Advances and Potentials
title_full The Management of Scabies in the 21st Century: Past, Advances and Potentials
title_fullStr The Management of Scabies in the 21st Century: Past, Advances and Potentials
title_full_unstemmed The Management of Scabies in the 21st Century: Past, Advances and Potentials
title_short The Management of Scabies in the 21st Century: Past, Advances and Potentials
title_sort management of scabies in the 21st century past advances and potentials
topic scabies
sarcoptes scabiei
neglected tropical disease
ivermectin
permethrin
moxidectin
acaricide discovery and development
ovicidal
url https://www.medicaljournals.se/acta/content/html/10.2340/00015555-3468
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