A phenyl-thiadiazolylidene-amine derivative ejects zinc from retroviral nucleocapsid zinc fingers and inactivates HIV virions

A phenyl-thiadiazolylidene-amine derivative ejects zinc from retroviral nucleocapsid zinc fingers and inactivates HIV virions

<p>Abstract</p> <p>Background</p> <p>Sexual acquisition of the human immunodeficiency virus (HIV) through mucosal transmission may be prevented by using topically applied agents that block HIV transmission from one individual to another. Therefore, virucidal agents that...

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Bibliographic Details
Main Authors: Vercruysse Thomas, Basta Beata, Dehaen Wim, Humbert Nicolas, Balzarini Jan, Debaene François, Sanglier-Cianférani Sarah, Pannecouque Christophe, Mély Yves, Daelemans Dirk
Format: Article
Language:English
Published: BMC 2012-11-01
Series:Retrovirology
Subjects:
HIV
Nucleocapsid
Virucide
Microbicide
Online Access:http://www.retrovirology.com/content/9/1/95

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