NADPH-Oxidase Derived Hydrogen Peroxide and Irs2b Facilitate Re-oxygenation-Induced Catch-Up Growth in Zebrafish Embryo

NADPH-Oxidase Derived Hydrogen Peroxide and Irs2b Facilitate Re-oxygenation-Induced Catch-Up Growth in Zebrafish Embryo

Oxygen deprivation induces multiple changes at the cellular and organismal levels, and its re-supply also brings another special physiological status. We have investigated the effects of hypoxia/re-oxygenation on embryonic growth using the zebrafish model: hypoxia slows embryonic growth, but re-oxyg...

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Bibliographic Details
Main Authors: Ayaka Zasu, Futa Hishima, Marion Thauvin, Yosuke Yoneyama, Yoichiro Kitani, Fumihiko Hakuno, Michel Volovitch, Shin-Ichiro Takahashi, Sophie Vriz, Christine Rampon, Hiroyasu Kamei
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Endocrinology
Subjects:
zebrafish
hypoxia
re-oxygenation
hydrogen peroxide
NADPH-oxidase
catch-up growth
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2022.929668/full

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