Promising Antibacterial and Antifungal Agents Based on Thiolated Vitamin K3 Analogs: Synthesis, Bioevaluation, Molecular Docking

Promising Antibacterial and Antifungal Agents Based on Thiolated Vitamin K3 Analogs: Synthesis, Bioevaluation, Molecular Docking

In the present study, we designed and synthesized thiolated <b>VK3</b> analogs (<b>VK3a–g</b>) along with an extensive antimicrobial study. After the evaluation of the antibacterial and antifungal activity against various bacterial and fungal strains, we presented an initial...

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Bibliographic Details
Main Authors: Hatice Yıldırım, Mahmut Yıldız, Nilüfer Bayrak, Emel Mataracı-Kara, Mohamed Osman Radwan, Ayse Tarbin Jannuzzi, Masami Otsuka, Mikako Fujita, Amaç Fatih TuYuN
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:Pharmaceuticals
Subjects:
antibacterial activity
antibiofilm activity
Vitamin K
<i>Staphylococcus aureus</i>
thymidylate kinase
Online Access:https://www.mdpi.com/1424-8247/15/5/586

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