The immune suppressive tumor microenvironment in multiple myeloma: The contribution of myeloid-derived suppressor cells

The immune suppressive tumor microenvironment in multiple myeloma: The contribution of myeloid-derived suppressor cells

Myeloid derived suppressors cells (MDSC) play major roles in regulating immune homeostasis and immune responses in many conditions, including cancer. MDSC interact with cancer cells within the tumor microenvironment (TME) with direct and indirect mechanisms: production of soluble factors and cytokin...

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Bibliographic Details
Main Authors:	Claudia Giannotta, Federica Autino, Massimo Massaia
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2023-01-01
Series:	Frontiers in Immunology
Subjects:	MDSC (myeloid-derived suppressor cell) TME (tumor microenvironment) multiple myeloma Immunothearpies immune suppression
Online Access:	https://www.frontiersin.org/articles/10.3389/fimmu.2022.1102471/full

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