Quantitative Trait Loci Associated with the Tocochromanol (Vitamin E) Pathway in Barley.
The Genome-Wide Association Studies approach was used to detect Quantitative Trait Loci associated with tocochromanol concentrations using a panel of 1,466 barley accessions. All major tocochromanol types- α-, β-, δ-, γ-tocopherol and tocotrienol- were assayed. We found 13 single nucleotide polymorp...
| Main Authors: | , , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Public Library of Science (PLoS)
2015-01-01
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| Series: | PLoS ONE |
| Online Access: | http://europepmc.org/articles/PMC4514886?pdf=render |
| _version_ | 1819200194933161984 |
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| author | Ryan C Graebner Mitchell Wise Alfonso Cuesta-Marcos Matthew Geniza Tom Blake Victoria C Blake Joshua Butler Shiaomen Chao David J Hole Rich Horsley Pankaj Jaiswal Don Obert Kevin P Smith Steven Ullrich Patrick M Hayes |
| author_facet | Ryan C Graebner Mitchell Wise Alfonso Cuesta-Marcos Matthew Geniza Tom Blake Victoria C Blake Joshua Butler Shiaomen Chao David J Hole Rich Horsley Pankaj Jaiswal Don Obert Kevin P Smith Steven Ullrich Patrick M Hayes |
| author_sort | Ryan C Graebner |
| collection | DOAJ |
| description | The Genome-Wide Association Studies approach was used to detect Quantitative Trait Loci associated with tocochromanol concentrations using a panel of 1,466 barley accessions. All major tocochromanol types- α-, β-, δ-, γ-tocopherol and tocotrienol- were assayed. We found 13 single nucleotide polymorphisms associated with the concentration of one or more of these tocochromanol forms in barley, seven of which were within 2 cM of sequences homologous to cloned genes associated with tocochromanol production in barley and/or other plants. These associations confirmed a prior report based on bi-parental QTL mapping. This knowledge will aid future efforts to better understand the role of tocochromanols in barley, with specific reference to abiotic stress resistance. It will also be useful in developing barley varieties with higher tocochromanol concentrations, although at current recommended daily consumption amounts, barley would not be an effective sole source of vitamin E. However, it could be an important contributor in the context of whole grains in a balanced diet. |
| first_indexed | 2024-12-23T03:28:22Z |
| format | Article |
| id | doaj.art-f0f3f43d42f5438ca0c92c96603b184a |
| institution | Directory Open Access Journal |
| issn | 1932-6203 |
| language | English |
| last_indexed | 2024-12-23T03:28:22Z |
| publishDate | 2015-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj.art-f0f3f43d42f5438ca0c92c96603b184a2022-12-21T18:01:47ZengPublic Library of Science (PLoS)PLoS ONE1932-62032015-01-01107e013376710.1371/journal.pone.0133767Quantitative Trait Loci Associated with the Tocochromanol (Vitamin E) Pathway in Barley.Ryan C GraebnerMitchell WiseAlfonso Cuesta-MarcosMatthew GenizaTom BlakeVictoria C BlakeJoshua ButlerShiaomen ChaoDavid J HoleRich HorsleyPankaj JaiswalDon ObertKevin P SmithSteven UllrichPatrick M HayesThe Genome-Wide Association Studies approach was used to detect Quantitative Trait Loci associated with tocochromanol concentrations using a panel of 1,466 barley accessions. All major tocochromanol types- α-, β-, δ-, γ-tocopherol and tocotrienol- were assayed. We found 13 single nucleotide polymorphisms associated with the concentration of one or more of these tocochromanol forms in barley, seven of which were within 2 cM of sequences homologous to cloned genes associated with tocochromanol production in barley and/or other plants. These associations confirmed a prior report based on bi-parental QTL mapping. This knowledge will aid future efforts to better understand the role of tocochromanols in barley, with specific reference to abiotic stress resistance. It will also be useful in developing barley varieties with higher tocochromanol concentrations, although at current recommended daily consumption amounts, barley would not be an effective sole source of vitamin E. However, it could be an important contributor in the context of whole grains in a balanced diet.http://europepmc.org/articles/PMC4514886?pdf=render |
| spellingShingle | Ryan C Graebner Mitchell Wise Alfonso Cuesta-Marcos Matthew Geniza Tom Blake Victoria C Blake Joshua Butler Shiaomen Chao David J Hole Rich Horsley Pankaj Jaiswal Don Obert Kevin P Smith Steven Ullrich Patrick M Hayes Quantitative Trait Loci Associated with the Tocochromanol (Vitamin E) Pathway in Barley. PLoS ONE |
| title | Quantitative Trait Loci Associated with the Tocochromanol (Vitamin E) Pathway in Barley. |
| title_full | Quantitative Trait Loci Associated with the Tocochromanol (Vitamin E) Pathway in Barley. |
| title_fullStr | Quantitative Trait Loci Associated with the Tocochromanol (Vitamin E) Pathway in Barley. |
| title_full_unstemmed | Quantitative Trait Loci Associated with the Tocochromanol (Vitamin E) Pathway in Barley. |
| title_short | Quantitative Trait Loci Associated with the Tocochromanol (Vitamin E) Pathway in Barley. |
| title_sort | quantitative trait loci associated with the tocochromanol vitamin e pathway in barley |
| url | http://europepmc.org/articles/PMC4514886?pdf=render |
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