Is sonic Hedgehog involved in human fracture healing? --a prospective study on local and systemic concentrations of SHH.

Is sonic Hedgehog involved in human fracture healing? --a prospective study on local and systemic concentrations of SHH.

INTRODUCTION: Sonic Hedgehog (SHH) is a new signalling pathway in bone repair. Evidence exist that SHH pathway plays a significant role in vasculogenesis and limb development during embryogenesis. Some in vitro and animal studies has already proven its potential for bone regeneration. However, no da...

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Bibliographic Details
Main Authors: Stefan Eipeldauer, Anita Thomas, Leonard Hoechtl-Lee, Mathias Kecht, Harald Binder, Julia Koettstorfer, Markus Gregori, Kambiz Sarahrudi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4263617?pdf=render

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