STING contributes to lipopolysaccharide-induced tubular cell inflammation and pyroptosis by activating endoplasmic reticulum stress in acute kidney injury

STING contributes to lipopolysaccharide-induced tubular cell inflammation and pyroptosis by activating endoplasmic reticulum stress in acute kidney injury

Abstract Recently, innate immunity and inflammation were recognized as the key factors for acute kidney injury (AKI) caused by sepsis, which is closely related to high mortality. Stimulator of interferon genes (STING) has emerged as a critical component of innate immune and inflammatory responses. H...

Full description

Bibliographic Details
Main Authors: Yun Cao, Xinghua Chen, Zijing Zhu, Zilv Luo, Yiqun Hao, Xueyan Yang, Jun Feng, Zongwei Zhang, Jijia Hu, Yonghong Jian, Jiefu Zhu, Wei Liang, Zhaowei Chen
Format: Article
Language:English
Published: Nature Publishing Group 2024-03-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-024-06600-1

Similar Items

Similar Items