Tuberculosis and HIV co-infection—focus on the Asia-Pacific region
Tuberculosis (TB) is the leading opportunistic disease and cause of death in patients with HIV infection. In 2013 there were 1.1 million new TB/HIV co-infected cases globally, accounting for 12% of incident TB cases and 360 000 deaths. The Asia-Pacific region, which contributes more than a half of a...
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| Format: | Article |
| Language: | English |
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Elsevier
2015-03-01
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| Series: | International Journal of Infectious Diseases |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1201971214017123 |
| _version_ | 1818236794405126144 |
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| author | Q.M. Trinh H.L. Nguyen V.N. Nguyen T.V.A. Nguyen V. Sintchenko B.J. Marais |
| author_facet | Q.M. Trinh H.L. Nguyen V.N. Nguyen T.V.A. Nguyen V. Sintchenko B.J. Marais |
| author_sort | Q.M. Trinh |
| collection | DOAJ |
| description | Tuberculosis (TB) is the leading opportunistic disease and cause of death in patients with HIV infection. In 2013 there were 1.1 million new TB/HIV co-infected cases globally, accounting for 12% of incident TB cases and 360 000 deaths. The Asia-Pacific region, which contributes more than a half of all TB cases worldwide, traditionally reports low TB/HIV co-infection rates. However, routine testing of TB patients for HIV infection is not universally implemented and the estimated prevalence of HIV in new TB cases increased to 6.3% in 2013. Although HIV infection rates have not seen the rapid rise observed in Sub-Saharan Africa, indications are that rates are increasing among specific high-risk groups. This paper reviews the risks of TB exposure and progression to disease, including the risk of TB recurrence, in this vulnerable population. There is urgency to scale up interventions such as intensified TB case-finding, isoniazid preventive therapy, and TB infection control, as well as HIV testing and improved access to antiretroviral treatment. Increased awareness and concerted action is required to reduce TB/HIV co-infection rates in the Asia-Pacific region and to improve the outcomes of people living with HIV. |
| first_indexed | 2024-12-12T12:15:31Z |
| format | Article |
| id | doaj.art-f0fd8759b0a145c2b7748c084cd82d78 |
| institution | Directory Open Access Journal |
| issn | 1201-9712 1878-3511 |
| language | English |
| last_indexed | 2024-12-12T12:15:31Z |
| publishDate | 2015-03-01 |
| publisher | Elsevier |
| record_format | Article |
| series | International Journal of Infectious Diseases |
| spelling | doaj.art-f0fd8759b0a145c2b7748c084cd82d782022-12-22T00:24:47ZengElsevierInternational Journal of Infectious Diseases1201-97121878-35112015-03-0132C17017810.1016/j.ijid.2014.11.023Tuberculosis and HIV co-infection—focus on the Asia-Pacific regionQ.M. Trinh0H.L. Nguyen1V.N. Nguyen2T.V.A. Nguyen3V. Sintchenko4B.J. Marais5Marie Bashir Institute for Infectious Diseases and Biosecurity (MBI), The University of Sydney, Sydney, AustraliaVietnam Administration of HIV/AIDS Control, Hanoi, VietnamVietnam National Lung Hospital, Hanoi, VietnamTuberculosis Laboratory, Vietnam National Institute of Hygiene and Epidemiology, Hanoi, VietnamMarie Bashir Institute for Infectious Diseases and Biosecurity (MBI), The University of Sydney, Sydney, AustraliaMarie Bashir Institute for Infectious Diseases and Biosecurity (MBI), The University of Sydney, Sydney, AustraliaTuberculosis (TB) is the leading opportunistic disease and cause of death in patients with HIV infection. In 2013 there were 1.1 million new TB/HIV co-infected cases globally, accounting for 12% of incident TB cases and 360 000 deaths. The Asia-Pacific region, which contributes more than a half of all TB cases worldwide, traditionally reports low TB/HIV co-infection rates. However, routine testing of TB patients for HIV infection is not universally implemented and the estimated prevalence of HIV in new TB cases increased to 6.3% in 2013. Although HIV infection rates have not seen the rapid rise observed in Sub-Saharan Africa, indications are that rates are increasing among specific high-risk groups. This paper reviews the risks of TB exposure and progression to disease, including the risk of TB recurrence, in this vulnerable population. There is urgency to scale up interventions such as intensified TB case-finding, isoniazid preventive therapy, and TB infection control, as well as HIV testing and improved access to antiretroviral treatment. Increased awareness and concerted action is required to reduce TB/HIV co-infection rates in the Asia-Pacific region and to improve the outcomes of people living with HIV.http://www.sciencedirect.com/science/article/pii/S1201971214017123TuberculosisHIVCo-infection |
| spellingShingle | Q.M. Trinh H.L. Nguyen V.N. Nguyen T.V.A. Nguyen V. Sintchenko B.J. Marais Tuberculosis and HIV co-infection—focus on the Asia-Pacific region International Journal of Infectious Diseases Tuberculosis HIV Co-infection |
| title | Tuberculosis and HIV co-infection—focus on the Asia-Pacific region |
| title_full | Tuberculosis and HIV co-infection—focus on the Asia-Pacific region |
| title_fullStr | Tuberculosis and HIV co-infection—focus on the Asia-Pacific region |
| title_full_unstemmed | Tuberculosis and HIV co-infection—focus on the Asia-Pacific region |
| title_short | Tuberculosis and HIV co-infection—focus on the Asia-Pacific region |
| title_sort | tuberculosis and hiv co infection focus on the asia pacific region |
| topic | Tuberculosis HIV Co-infection |
| url | http://www.sciencedirect.com/science/article/pii/S1201971214017123 |
| work_keys_str_mv | AT qmtrinh tuberculosisandhivcoinfectionfocusontheasiapacificregion AT hlnguyen tuberculosisandhivcoinfectionfocusontheasiapacificregion AT vnnguyen tuberculosisandhivcoinfectionfocusontheasiapacificregion AT tvanguyen tuberculosisandhivcoinfectionfocusontheasiapacificregion AT vsintchenko tuberculosisandhivcoinfectionfocusontheasiapacificregion AT bjmarais tuberculosisandhivcoinfectionfocusontheasiapacificregion |