Ovarian Cancer Cell Adhesion/Migration Dynamics on Micro-Structured Laminin Gradients Fabricated by Multiphoton Excited Photochemistry

Ovarian Cancer Cell Adhesion/Migration Dynamics on Micro-Structured Laminin Gradients Fabricated by Multiphoton Excited Photochemistry

Haptotaxis, i.e., cell migration in response to adhesive gradients, has been previously implicated in cancer metastasis. A better understanding of cell migration dynamics and their regulation could ultimately lead to new drug targets, especially for cancers with poor prognoses, such as ovarian cance...

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Bibliographic Details
Main Authors: Ruei-Yu He, Visar Ajeti, Shean-Jen Chen, Molly A. Brewer, Paul J. Campagnola
Format: Article
Language:English
Published: MDPI AG 2015-07-01
Series:Bioengineering
Subjects:
ovarian cancer
ECM
haptotaxis
contact guidance
morphology
cytoskeleton
Online Access:http://www.mdpi.com/2306-5354/2/3/139

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