Participation in a single-blinded pediatric therapeutic strategy study for juvenile idiopathic arthritis: are parents and patient-participants in equipoise?

Participation in a single-blinded pediatric therapeutic strategy study for juvenile idiopathic arthritis: are parents and patient-participants in equipoise?

Abstract Background Genuine uncertainty on superiority of one intervention over the other is called equipoise. Physician-investigators in randomized controlled trials (RCT) need equipoise at least in studies with more than minimal risks. Ideally, this equipoise is also present in patient-participant...

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Bibliographic Details
Main Authors: Petra C. E. Hissink Muller, Bahar Yildiz, Cornelia F. Allaart, Danielle M. C. Brinkman, Marion van Rossum, Lisette W. A. van Suijlekom-Smit, J. Merlijn van den Berg, Rebecca ten Cate, Martine C. de Vries
Format: Article
Language:English
Published: BMC 2018-12-01
Series:BMC Medical Ethics
Subjects:
Equipoise
Clinical trial
Juvenile idiopathic arthritis
Therapeutic strategy study
Biologicals
Treatment-to-target
Online Access:http://link.springer.com/article/10.1186/s12910-018-0336-8

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