Mucosal relapse of visceral leishmaniasis in a child treated with anti-TNFα
Visceral leishmaniasis is an enzootic parasitosis present across the Mediterranean Basin. Some consider it an opportunistic parasite. We report the case of a girl treated with anti-tumour necrosis factor alpha (anti-TNFα) for juvenile idiopathic arthritis who had previously presented with visceral l...
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| Format: | Article |
| Language: | English |
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Elsevier
2015-04-01
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| Series: | International Journal of Infectious Diseases |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1201971214017548 |
| _version_ | 1818230518647357440 |
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| author | E. Jeziorski J. Dereure G. Mac Bullen C. Blanchet C. Ludwig V. Costes M. Rodière |
| author_facet | E. Jeziorski J. Dereure G. Mac Bullen C. Blanchet C. Ludwig V. Costes M. Rodière |
| author_sort | E. Jeziorski |
| collection | DOAJ |
| description | Visceral leishmaniasis is an enzootic parasitosis present across the Mediterranean Basin. Some consider it an opportunistic parasite. We report the case of a girl treated with anti-tumour necrosis factor alpha (anti-TNFα) for juvenile idiopathic arthritis who had previously presented with visceral leishmaniasis. Two and a half years later, she presented a tumour-like mass in the nasal mucous membrane caused by Leishmania parasites. Leishmania infantum is classically responsible for visceral leishmaniasis, but pure mucocutaneous leishmaniasis has also been described. To our knowledge, this is the first observation of a recurrence of visceral leishmaniasis in the mucocutaneous form. The occurrence of atypical forms and presentations in those on anti-TNF therapy should be considered. |
| first_indexed | 2024-12-12T10:35:46Z |
| format | Article |
| id | doaj.art-f0ff390567bc4af6a09700cc10e3488b |
| institution | Directory Open Access Journal |
| issn | 1201-9712 1878-3511 |
| language | English |
| last_indexed | 2024-12-12T10:35:46Z |
| publishDate | 2015-04-01 |
| publisher | Elsevier |
| record_format | Article |
| series | International Journal of Infectious Diseases |
| spelling | doaj.art-f0ff390567bc4af6a09700cc10e3488b2022-12-22T00:27:13ZengElsevierInternational Journal of Infectious Diseases1201-97121878-35112015-04-0133C13513610.1016/j.ijid.2014.12.036Mucosal relapse of visceral leishmaniasis in a child treated with anti-TNFαE. Jeziorski0J. Dereure1G. Mac Bullen2C. Blanchet3C. Ludwig4V. Costes5M. Rodière6Centre Hospitalier Régional Universitaire de Montpellier, Hôpital Arnaud de Villeneuve, Service de Pédiatrie Générale et Infectiologie et Immunologie Clinique, 371, avenue du Doyen Gaston Giraud, 34295 Montpellier cedex 5, FranceCentre Hospitalier Régional Universitaire de Montpellier, Laboratoire de Parasitologie-Mycologie, Montpellier, FranceCentre Hospitalier Régional Universitaire de Montpellier, Hôpital Lapeyronnie, Service des Urgences Pédiatriques, Montpellier, FranceCentre Hospitalier Régional Universitaire de Montpellier, Hôpital Gui de Chauliac, Service d’Oto-Rhino-Laryngologie, Montpellier, FranceCentre Hospitalier Régional Universitaire de Montpellier, Hôpital Arnaud de Villeneuve, Service de Pédiatrie Générale et Infectiologie et Immunologie Clinique, 371, avenue du Doyen Gaston Giraud, 34295 Montpellier cedex 5, FranceCentre Hospitalier Régional Universitaire de Montpellier, Hôpital Gui de Chauliac, Service d’Anatomopathologie, Montpellier, FranceCentre Hospitalier Régional Universitaire de Montpellier, Hôpital Arnaud de Villeneuve, Service de Pédiatrie Générale et Infectiologie et Immunologie Clinique, 371, avenue du Doyen Gaston Giraud, 34295 Montpellier cedex 5, FranceVisceral leishmaniasis is an enzootic parasitosis present across the Mediterranean Basin. Some consider it an opportunistic parasite. We report the case of a girl treated with anti-tumour necrosis factor alpha (anti-TNFα) for juvenile idiopathic arthritis who had previously presented with visceral leishmaniasis. Two and a half years later, she presented a tumour-like mass in the nasal mucous membrane caused by Leishmania parasites. Leishmania infantum is classically responsible for visceral leishmaniasis, but pure mucocutaneous leishmaniasis has also been described. To our knowledge, this is the first observation of a recurrence of visceral leishmaniasis in the mucocutaneous form. The occurrence of atypical forms and presentations in those on anti-TNF therapy should be considered.http://www.sciencedirect.com/science/article/pii/S1201971214017548LeishmaniasisAnti-TNF therapeutic |
| spellingShingle | E. Jeziorski J. Dereure G. Mac Bullen C. Blanchet C. Ludwig V. Costes M. Rodière Mucosal relapse of visceral leishmaniasis in a child treated with anti-TNFα International Journal of Infectious Diseases Leishmaniasis Anti-TNF therapeutic |
| title | Mucosal relapse of visceral leishmaniasis in a child treated with anti-TNFα |
| title_full | Mucosal relapse of visceral leishmaniasis in a child treated with anti-TNFα |
| title_fullStr | Mucosal relapse of visceral leishmaniasis in a child treated with anti-TNFα |
| title_full_unstemmed | Mucosal relapse of visceral leishmaniasis in a child treated with anti-TNFα |
| title_short | Mucosal relapse of visceral leishmaniasis in a child treated with anti-TNFα |
| title_sort | mucosal relapse of visceral leishmaniasis in a child treated with anti tnfα |
| topic | Leishmaniasis Anti-TNF therapeutic |
| url | http://www.sciencedirect.com/science/article/pii/S1201971214017548 |
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