Emulgels: Promising Carrier Systems for Food Ingredients and Drugs
Novel delivery systems for cosmetics, drugs, and food ingredients are of great scientific and industrial interest due to their ability to incorporate and protect active substances, thus improving their selectivity, bioavailability, and efficacy. Emulgels are emerging carrier systems that represent a...
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Format: | Article |
Language: | English |
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MDPI AG
2023-05-01
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Series: | Polymers |
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Online Access: | https://www.mdpi.com/2073-4360/15/10/2302 |
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author | Jovana Milutinov Veljko Krstonošić Dejan Ćirin Nebojša Pavlović |
author_facet | Jovana Milutinov Veljko Krstonošić Dejan Ćirin Nebojša Pavlović |
author_sort | Jovana Milutinov |
collection | DOAJ |
description | Novel delivery systems for cosmetics, drugs, and food ingredients are of great scientific and industrial interest due to their ability to incorporate and protect active substances, thus improving their selectivity, bioavailability, and efficacy. Emulgels are emerging carrier systems that represent a mixture of emulsion and gel, which are particularly significant for the delivery of hydrophobic substances. However, the proper selection of main constituents determines the stability and efficacy of emulgels. Emulgels are dual-controlled release systems, where the oil phase is utilized as a carrier for hydrophobic substances and it determines the occlusive and sensory properties of the product. The emulsifiers are used to promote emulsification during production and to ensure emulsion stability. The choice of emulsifying agents is based on their capacity to emulsify, their toxicity, and their route of administration. Generally, gelling agents are used to increase the consistency of formulation and improve sensory properties by making these systems thixotropic. The gelling agents also impact the release of active substances from the formulation and stability of the system. Therefore, the aim of this review is to gain new insights into emulgel formulations, including the components selection, methods of preparation, and characterization, which are based on recent advances in research studies. |
first_indexed | 2024-03-11T03:22:56Z |
format | Article |
id | doaj.art-f102a6c2703746cd9d585d19fc64a0c6 |
institution | Directory Open Access Journal |
issn | 2073-4360 |
language | English |
last_indexed | 2024-03-11T03:22:56Z |
publishDate | 2023-05-01 |
publisher | MDPI AG |
record_format | Article |
series | Polymers |
spelling | doaj.art-f102a6c2703746cd9d585d19fc64a0c62023-11-18T02:58:09ZengMDPI AGPolymers2073-43602023-05-011510230210.3390/polym15102302Emulgels: Promising Carrier Systems for Food Ingredients and DrugsJovana Milutinov0Veljko Krstonošić1Dejan Ćirin2Nebojša Pavlović3Department of Pharmacy, Faculty of Medicine, University of Novi Sad, Hajduk Veljkova 3, 21000 Novi Sad, SerbiaDepartment of Pharmacy, Faculty of Medicine, University of Novi Sad, Hajduk Veljkova 3, 21000 Novi Sad, SerbiaDepartment of Pharmacy, Faculty of Medicine, University of Novi Sad, Hajduk Veljkova 3, 21000 Novi Sad, SerbiaDepartment of Pharmacy, Faculty of Medicine, University of Novi Sad, Hajduk Veljkova 3, 21000 Novi Sad, SerbiaNovel delivery systems for cosmetics, drugs, and food ingredients are of great scientific and industrial interest due to their ability to incorporate and protect active substances, thus improving their selectivity, bioavailability, and efficacy. Emulgels are emerging carrier systems that represent a mixture of emulsion and gel, which are particularly significant for the delivery of hydrophobic substances. However, the proper selection of main constituents determines the stability and efficacy of emulgels. Emulgels are dual-controlled release systems, where the oil phase is utilized as a carrier for hydrophobic substances and it determines the occlusive and sensory properties of the product. The emulsifiers are used to promote emulsification during production and to ensure emulsion stability. The choice of emulsifying agents is based on their capacity to emulsify, their toxicity, and their route of administration. Generally, gelling agents are used to increase the consistency of formulation and improve sensory properties by making these systems thixotropic. The gelling agents also impact the release of active substances from the formulation and stability of the system. Therefore, the aim of this review is to gain new insights into emulgel formulations, including the components selection, methods of preparation, and characterization, which are based on recent advances in research studies.https://www.mdpi.com/2073-4360/15/10/2302emulsion gelsdelivery systemsdrug deliverytopical formulations |
spellingShingle | Jovana Milutinov Veljko Krstonošić Dejan Ćirin Nebojša Pavlović Emulgels: Promising Carrier Systems for Food Ingredients and Drugs Polymers emulsion gels delivery systems drug delivery topical formulations |
title | Emulgels: Promising Carrier Systems for Food Ingredients and Drugs |
title_full | Emulgels: Promising Carrier Systems for Food Ingredients and Drugs |
title_fullStr | Emulgels: Promising Carrier Systems for Food Ingredients and Drugs |
title_full_unstemmed | Emulgels: Promising Carrier Systems for Food Ingredients and Drugs |
title_short | Emulgels: Promising Carrier Systems for Food Ingredients and Drugs |
title_sort | emulgels promising carrier systems for food ingredients and drugs |
topic | emulsion gels delivery systems drug delivery topical formulations |
url | https://www.mdpi.com/2073-4360/15/10/2302 |
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