Emulgels: Promising Carrier Systems for Food Ingredients and Drugs

Novel delivery systems for cosmetics, drugs, and food ingredients are of great scientific and industrial interest due to their ability to incorporate and protect active substances, thus improving their selectivity, bioavailability, and efficacy. Emulgels are emerging carrier systems that represent a...

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Main Authors: Jovana Milutinov, Veljko Krstonošić, Dejan Ćirin, Nebojša Pavlović
Format: Article
Language:English
Published: MDPI AG 2023-05-01
Series:Polymers
Subjects:
Online Access:https://www.mdpi.com/2073-4360/15/10/2302
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author Jovana Milutinov
Veljko Krstonošić
Dejan Ćirin
Nebojša Pavlović
author_facet Jovana Milutinov
Veljko Krstonošić
Dejan Ćirin
Nebojša Pavlović
author_sort Jovana Milutinov
collection DOAJ
description Novel delivery systems for cosmetics, drugs, and food ingredients are of great scientific and industrial interest due to their ability to incorporate and protect active substances, thus improving their selectivity, bioavailability, and efficacy. Emulgels are emerging carrier systems that represent a mixture of emulsion and gel, which are particularly significant for the delivery of hydrophobic substances. However, the proper selection of main constituents determines the stability and efficacy of emulgels. Emulgels are dual-controlled release systems, where the oil phase is utilized as a carrier for hydrophobic substances and it determines the occlusive and sensory properties of the product. The emulsifiers are used to promote emulsification during production and to ensure emulsion stability. The choice of emulsifying agents is based on their capacity to emulsify, their toxicity, and their route of administration. Generally, gelling agents are used to increase the consistency of formulation and improve sensory properties by making these systems thixotropic. The gelling agents also impact the release of active substances from the formulation and stability of the system. Therefore, the aim of this review is to gain new insights into emulgel formulations, including the components selection, methods of preparation, and characterization, which are based on recent advances in research studies.
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spelling doaj.art-f102a6c2703746cd9d585d19fc64a0c62023-11-18T02:58:09ZengMDPI AGPolymers2073-43602023-05-011510230210.3390/polym15102302Emulgels: Promising Carrier Systems for Food Ingredients and DrugsJovana Milutinov0Veljko Krstonošić1Dejan Ćirin2Nebojša Pavlović3Department of Pharmacy, Faculty of Medicine, University of Novi Sad, Hajduk Veljkova 3, 21000 Novi Sad, SerbiaDepartment of Pharmacy, Faculty of Medicine, University of Novi Sad, Hajduk Veljkova 3, 21000 Novi Sad, SerbiaDepartment of Pharmacy, Faculty of Medicine, University of Novi Sad, Hajduk Veljkova 3, 21000 Novi Sad, SerbiaDepartment of Pharmacy, Faculty of Medicine, University of Novi Sad, Hajduk Veljkova 3, 21000 Novi Sad, SerbiaNovel delivery systems for cosmetics, drugs, and food ingredients are of great scientific and industrial interest due to their ability to incorporate and protect active substances, thus improving their selectivity, bioavailability, and efficacy. Emulgels are emerging carrier systems that represent a mixture of emulsion and gel, which are particularly significant for the delivery of hydrophobic substances. However, the proper selection of main constituents determines the stability and efficacy of emulgels. Emulgels are dual-controlled release systems, where the oil phase is utilized as a carrier for hydrophobic substances and it determines the occlusive and sensory properties of the product. The emulsifiers are used to promote emulsification during production and to ensure emulsion stability. The choice of emulsifying agents is based on their capacity to emulsify, their toxicity, and their route of administration. Generally, gelling agents are used to increase the consistency of formulation and improve sensory properties by making these systems thixotropic. The gelling agents also impact the release of active substances from the formulation and stability of the system. Therefore, the aim of this review is to gain new insights into emulgel formulations, including the components selection, methods of preparation, and characterization, which are based on recent advances in research studies.https://www.mdpi.com/2073-4360/15/10/2302emulsion gelsdelivery systemsdrug deliverytopical formulations
spellingShingle Jovana Milutinov
Veljko Krstonošić
Dejan Ćirin
Nebojša Pavlović
Emulgels: Promising Carrier Systems for Food Ingredients and Drugs
Polymers
emulsion gels
delivery systems
drug delivery
topical formulations
title Emulgels: Promising Carrier Systems for Food Ingredients and Drugs
title_full Emulgels: Promising Carrier Systems for Food Ingredients and Drugs
title_fullStr Emulgels: Promising Carrier Systems for Food Ingredients and Drugs
title_full_unstemmed Emulgels: Promising Carrier Systems for Food Ingredients and Drugs
title_short Emulgels: Promising Carrier Systems for Food Ingredients and Drugs
title_sort emulgels promising carrier systems for food ingredients and drugs
topic emulsion gels
delivery systems
drug delivery
topical formulations
url https://www.mdpi.com/2073-4360/15/10/2302
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AT nebojsapavlovic emulgelspromisingcarriersystemsforfoodingredientsanddrugs