Can glass polyalkenoate (glass-ionomer) dental cements be considered bioactive? A review
Objectives: This paper reviews the chemical behaviour of glass polyalkenoate (glass-ionomer) dental cements, both conventional and resin-modified, in contact with natural tissues, with the aim of determining whether these materials can be considered to be bioactive. Data: Relevant papers describing...
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| Format: | Article |
| Language: | English |
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Elsevier
2024-02-01
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| Series: | Heliyon |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2405844024012702 |
| _version_ | 1797304517119705088 |
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| author | John W. Nicholson Sharanbir K. Sidhu Beata Czarnecka |
| author_facet | John W. Nicholson Sharanbir K. Sidhu Beata Czarnecka |
| author_sort | John W. Nicholson |
| collection | DOAJ |
| description | Objectives: This paper reviews the chemical behaviour of glass polyalkenoate (glass-ionomer) dental cements, both conventional and resin-modified, in contact with natural tissues, with the aim of determining whether these materials can be considered to be bioactive. Data: Relevant papers describing the behaviour of bioactive glasses and ceramics, and glass-ionomer (glass polyalkenoate) cements have been identified using PubMed and Science Direct. This has allowed a comparison to be made between the behaviour of glass-ionomers and the speciality glasses and ceramics that are widely classified as bioactive, a designation considered valid for over fifty years. More recent papers concerning bioactive metals and polymers have also been studied and both in vitro and in vivo studies are included. Sources: Have included general papers on the chemistry and biological behaviour of bioactive glasses and ceramics, as well as papers on glass-ionomers dealing with (i) ion release, (ii) bonding to the surface of teeth, (iii) influence on surrounding pH and (iv) interaction with bone. Conclusion: The literature shows that glass-ionomers (glass polyalkenoates) have three types of behaviour that are similar to those of bioactive glasses as follows: Formation of direct bonds to living tissue (teeth and bones) without fibrous capsule; release of biologically beneficial ions; and change of the local pH. However, in in vitro tests, they do not cause calcium phosphate to precipitate from solutions of simulated body fluid, SBF. Despite this, studies show that, in patients, glass-ionomers interact chemically with hard tissues and this suggests that may indeed be considered bioactive. |
| first_indexed | 2024-03-08T00:11:39Z |
| format | Article |
| id | doaj.art-f10379ec27a74c568be6e614146556ee |
| institution | Directory Open Access Journal |
| issn | 2405-8440 |
| language | English |
| last_indexed | 2024-03-08T00:11:39Z |
| publishDate | 2024-02-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Heliyon |
| spelling | doaj.art-f10379ec27a74c568be6e614146556ee2024-02-17T06:40:12ZengElsevierHeliyon2405-84402024-02-01103e25239Can glass polyalkenoate (glass-ionomer) dental cements be considered bioactive? A reviewJohn W. Nicholson0Sharanbir K. Sidhu1Beata Czarnecka2Bluefield Centre for Biomaterials, 152-160 City Road, London EC1V 2NX, UK and Dental Physical Sciences, Institute of Dentistry, Barts & The London School of Medicine and Dentistry, Queen Mary University of London, Mile End Road, London, E1 4NS, UK; Corresponding author.Centre for Oral Bioengineering, Institute of Dentistry, Barts & The London School of Medicine and Dentistry, Queen Mary University of London, Turner Street, London E1 2AD, UKDepartment of Biomaterials and Experimental Dentistry, Poznań University of Medical Sciences, Ul. Bukowska 70, 60-812 Poznań, PolandObjectives: This paper reviews the chemical behaviour of glass polyalkenoate (glass-ionomer) dental cements, both conventional and resin-modified, in contact with natural tissues, with the aim of determining whether these materials can be considered to be bioactive. Data: Relevant papers describing the behaviour of bioactive glasses and ceramics, and glass-ionomer (glass polyalkenoate) cements have been identified using PubMed and Science Direct. This has allowed a comparison to be made between the behaviour of glass-ionomers and the speciality glasses and ceramics that are widely classified as bioactive, a designation considered valid for over fifty years. More recent papers concerning bioactive metals and polymers have also been studied and both in vitro and in vivo studies are included. Sources: Have included general papers on the chemistry and biological behaviour of bioactive glasses and ceramics, as well as papers on glass-ionomers dealing with (i) ion release, (ii) bonding to the surface of teeth, (iii) influence on surrounding pH and (iv) interaction with bone. Conclusion: The literature shows that glass-ionomers (glass polyalkenoates) have three types of behaviour that are similar to those of bioactive glasses as follows: Formation of direct bonds to living tissue (teeth and bones) without fibrous capsule; release of biologically beneficial ions; and change of the local pH. However, in in vitro tests, they do not cause calcium phosphate to precipitate from solutions of simulated body fluid, SBF. Despite this, studies show that, in patients, glass-ionomers interact chemically with hard tissues and this suggests that may indeed be considered bioactive.http://www.sciencedirect.com/science/article/pii/S2405844024012702Glass-ionomerPolyalkenoateBioactivityBioactive glassIon-releasepH change |
| spellingShingle | John W. Nicholson Sharanbir K. Sidhu Beata Czarnecka Can glass polyalkenoate (glass-ionomer) dental cements be considered bioactive? A review Heliyon Glass-ionomer Polyalkenoate Bioactivity Bioactive glass Ion-release pH change |
| title | Can glass polyalkenoate (glass-ionomer) dental cements be considered bioactive? A review |
| title_full | Can glass polyalkenoate (glass-ionomer) dental cements be considered bioactive? A review |
| title_fullStr | Can glass polyalkenoate (glass-ionomer) dental cements be considered bioactive? A review |
| title_full_unstemmed | Can glass polyalkenoate (glass-ionomer) dental cements be considered bioactive? A review |
| title_short | Can glass polyalkenoate (glass-ionomer) dental cements be considered bioactive? A review |
| title_sort | can glass polyalkenoate glass ionomer dental cements be considered bioactive a review |
| topic | Glass-ionomer Polyalkenoate Bioactivity Bioactive glass Ion-release pH change |
| url | http://www.sciencedirect.com/science/article/pii/S2405844024012702 |
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