Clock gene variation in type 2 diabetes: a review

Diabetes mellitus type 2 is a long-standing metabolic disorder that is exemplify by high blood sugar, insulin resistance, and comparative lack of insulin. General symptoms include increased thirst, frequent urination, and unsolved weight loss. Type 2 diabetes is mainly due to obesity and not suffici...

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Main Authors: Nushrat Parveen, Trilochan Satapathy, Pushpa Prasad, Amit Roy
Format: Article
Language:English
Published: Creative Pharma Assent 2015-01-01
Series:Journal of Applied Pharmaceutical Research
Subjects:
Online Access:https://japtronline.com/index.php/joapr/article/view/44
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author Nushrat Parveen
Trilochan Satapathy
Pushpa Prasad
Amit Roy
author_facet Nushrat Parveen
Trilochan Satapathy
Pushpa Prasad
Amit Roy
author_sort Nushrat Parveen
collection DOAJ
description Diabetes mellitus type 2 is a long-standing metabolic disorder that is exemplify by high blood sugar, insulin resistance, and comparative lack of insulin. General symptoms include increased thirst, frequent urination, and unsolved weight loss. Type 2 diabetes is mainly due to obesity and not sufficient work out in public who are heritably prone. Circadian clocks are significant to keep the moment in the sequence of physiological practice, series of behaviour and metabolism. The plasma level of glucose and numerous hormones implicated in glucose homeostasis for example insulin and glucagon exhibit circadian variation. Circadian desynchrony, a feature of alter occupation elevated-fat diet feed and sleep distraction in individual have been linked with metabolic disorders for instance obesity and type 2 diabetes. Circadian rhythm distraction can cause different fitness disarray. Current reading has discovered a seal connection among the pathophysiology of metabolic condition, which is characterized by obesity and hyperglycemia, and the operation of interior molecular clocks
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spelling doaj.art-f103b05050f64a9397adc877af19a3972022-12-21T22:42:28ZengCreative Pharma AssentJournal of Applied Pharmaceutical Research2348-03352015-01-0131010344Clock gene variation in type 2 diabetes: a reviewNushrat Parveen0Trilochan Satapathy1Pushpa Prasad2Amit Roy3Columbia Institute of Pharmacy, Vill. Tekari, Near Vidhan Sabha, Raipur (CG) 493111Columbia Institute of Pharmacy, Vill. Tekari, Near Vidhan Sabha, Raipur (CG) 493111Columbia Institute of Pharmacy, Vill. Tekari, Near Vidhan Sabha, Raipur (CG) 493111Columbia Institute of Pharmacy, Vill. Tekari, Near Vidhan Sabha, Raipur (CG) 493111Diabetes mellitus type 2 is a long-standing metabolic disorder that is exemplify by high blood sugar, insulin resistance, and comparative lack of insulin. General symptoms include increased thirst, frequent urination, and unsolved weight loss. Type 2 diabetes is mainly due to obesity and not sufficient work out in public who are heritably prone. Circadian clocks are significant to keep the moment in the sequence of physiological practice, series of behaviour and metabolism. The plasma level of glucose and numerous hormones implicated in glucose homeostasis for example insulin and glucagon exhibit circadian variation. Circadian desynchrony, a feature of alter occupation elevated-fat diet feed and sleep distraction in individual have been linked with metabolic disorders for instance obesity and type 2 diabetes. Circadian rhythm distraction can cause different fitness disarray. Current reading has discovered a seal connection among the pathophysiology of metabolic condition, which is characterized by obesity and hyperglycemia, and the operation of interior molecular clockshttps://japtronline.com/index.php/joapr/article/view/44clock genesdiabetes mellituspathophysiologysingle nucleotide polymorphismsobesity
spellingShingle Nushrat Parveen
Trilochan Satapathy
Pushpa Prasad
Amit Roy
Clock gene variation in type 2 diabetes: a review
Journal of Applied Pharmaceutical Research
clock genes
diabetes mellitus
pathophysiology
single nucleotide polymorphisms
obesity
title Clock gene variation in type 2 diabetes: a review
title_full Clock gene variation in type 2 diabetes: a review
title_fullStr Clock gene variation in type 2 diabetes: a review
title_full_unstemmed Clock gene variation in type 2 diabetes: a review
title_short Clock gene variation in type 2 diabetes: a review
title_sort clock gene variation in type 2 diabetes a review
topic clock genes
diabetes mellitus
pathophysiology
single nucleotide polymorphisms
obesity
url https://japtronline.com/index.php/joapr/article/view/44
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